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  1. Article

    Open Access

    Establishment of primary prostate epithelial and tumorigenic cell lines using a non-viral immortalization approach

    Research on prostate cancer is mostly performed using cell lines derived from metastatic disease, not reflecting stages of tumor initiation or early progression. Establishment of cancer cell lines derived from...

    Simon Lange, Anna Kuntze, Neele Wüstmann, Theresa Reckers… in Biological Research (2024)

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  2. Article

    Open Access

    Co-expression and clinical utility of AR-FL and AR splice variants AR-V3, AR-V7 and AR-V9 in prostate cancer

    Androgen receptor (AR) splice variants (AR-Vs) have been discussed as a biomarker in prostate cancer (PC). However, some reports question the predictive property of AR-Vs. From a mechanistic perspective, the c...

    Neele Wüstmann, Konstantin Seitzer, Verena Humberg, Julia Vieler… in Biomarker Research (2023)

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  3. Article

    Open Access

    Comparison of circulating tumor cells and AR-V7 as clinical biomarker in metastatic castration-resistant prostate cancer patients

    Biomarker in metastatic castration resistant prostate cancer (mCRPC) treatment are rare. We aimed to compare the clinical value of circulating tumor cells (CTCs) and androgen receptor splice variant 7 (AR-V7) ...

    Katrin Schlack, Konstantin Seitzer, Neele Wüstmann, Verena Humberg… in Scientific Reports (2022)

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