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  1. Article

    Open Access

    Simultaneous boost radiotherapy versus conventional dose radiotherapy for patients with newly diagnosed glioblastoma: a multi-institutional analysis

    We compared survival outcomes of high-dose concomitant boost radiotherapy (HDCBRT) and conventional dose radiotherapy (CRT) for newly diagnosed glioblastoma (GB). Patients treated with intensity-modulated radi...

    Seiya Takano, Natsuo Tomita, Mayu Kuno, Masanari Niwa, Akira Torii in Scientific Reports (2024)

  2. Article

    Open Access

    Impact of radiation doses on clinical relapse of biochemically recurrent prostate cancer after prostatectomy

    The relationship between radiation doses and clinical relapse in patients receiving salvage radiotherapy (SRT) for biochemical recurrence (BCR) after radical prostatectomy (RP) remains unclear. We identified 2...

    Seiya Takano, Natsuo Tomita, Masanari Niwa, Akira Torii in Scientific Reports (2024)

  3. Article

    Open Access

    Daily irradiation versus irradiation at two- to three-day intervals in stereotactic radiotherapy for patients with 1-5 brain metastases: study protocol for a multicenter open-label randomized phase II trial

    Radiobiological daily changes within tumors are considered to be quite different between stereotactic radiotherapy (SRT) (e.g., 50 Gy in 4 fractions) and conventional radiotherapy (e.g., 60 Gy in 30 fractions)...

    Natsuo Tomita, Hiromichi Ishiyama, Chiyoko Makita, Yukihiko Ohshima in BMC Cancer (2022)

  4. Article

    Open Access

    Relationship between radiation doses to heart substructures and radiation pneumonitis in patients with thymic epithelial tumors

    Radiation doses to the heart are potentially high in patients undergoing radiotherapy for thymoma or thymic carcinoma because of their origin site and propensity for pericardial invasion. We investigated poten...

    Natsuo Tomita, Katsuhiro Okuda, Yasutaka Ogawa, Masato Iida in Scientific Reports (2020)

  5. Article

    Open Access

    Impact of advanced radiotherapy techniques and dose intensification on toxicity of salvage radiotherapy after radical prostatectomy

    The safety and efficacy of dose-escalated radiotherapy with intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) remain unclear in salvage radiotherapy (SRT) after radical prostatectomy...

    Natsuo Tomita, Kaoru Uchiyama, Tomoki Mizuno, Mikiko Imai in Scientific Reports (2020)

  6. Article

    Open Access

    Repeat stereotactic body radiotherapy (SBRT) for local recurrence of non-small cell lung cancer and lung metastasis after first SBRT

    This study evaluated the safety and efficacy of repeat SBRT for local recurrence of stage I non-small-cell lung cancer (NSCLC) and solitary lung metastasis.

    Yasutaka Ogawa, Yuta Shibamoto, Chisa Hashizume, Takuhito Kondo in Radiation Oncology (2018)

  7. Article

    Open Access

    Efficacy of virtual block objects in reducing the lung dose in helical tomotherapy planning for cervical oesophageal cancer: a planning study

    Intensity-modulated radiotherapy is useful for cervical oesophageal carcinoma (CEC); however, increasing low-dose exposure to the lung may lead to radiation pneumonitis. Nevertheless, an irradiation technique ...

    Makoto Ito, Hidetoshi Shimizu, Takahiro Aoyama, Hiroyuki Tachibana in Radiation Oncology (2018)

  8. No Access

    Article

    High-dose radiotherapy with helical tomotherapy and long-term androgen deprivation therapy for prostate cancer: 5-year outcomes

    We aimed to examine outcomes of high-dose radiotherapy with helical tomotherapy (HT) and long-term androgen deprivation therapy (ADT) for T1–4N0M0 prostate cancer.

    Natsuo Tomita, Norihito Soga, Yuji Ogura in Journal of Cancer Research and Clinical On… (2016)

  9. Article

    Open Access

    Efficacy of palliative radiotherapy for gastric bleeding in patients with unresectable advanced gastric cancer: a retrospective cohort study

    Bleeding negatively impacts quality of life in patients with unresectable advanced gastric cancer and has the potential to be lethal. When blood transfusion and endoscopic hemostasis are unsuccessful to stop b...

    Chihiro Kondoh, Kohei Shitara, Motoo Nomura, Daisuke Takahari in BMC Palliative Care (2015)

  10. No Access

    Article

    A case of severe hemoptysis after stereotactic body radiotherapy for peripherally located stage I non-small cell lung cancer

    In stereotactic body radiotherapy (SBRT) for centrally located non-small cell lung carcinoma (NSCLC), severe hemoptysis has been reported in several studies. We report here a rare case of hemoptysis after SBRT...

    Kana Kimura, Natsuo Tomita, Arisa Shimizu, Yozo Sato in Japanese Journal of Radiology (2015)

  11. No Access

    Chapter

    Radiobiology for IMRT

    Since the dose delivery pattern is different between intensity-modulated radiotherapy (IMRT) and conventional radiation, radiobiological assessment of the physical dose delivered by IMRT is considered necessar...

    Yuta Shibamoto, Chikao Sugie, Hiroyuki Ogino in Intensity-Modulated Radiation Therapy (2015)

  12. No Access

    Article

    Preliminary results of intensity-modulated radiation therapy with helical tomotherapy for prostate cancer

    We present the preliminary results of intensity-modulated radiation therapy with helical tomotherapy (HT) for clinically localized prostate cancer.

    Natsuo Tomita, Norihito Soga, Yuji Ogura in Journal of Cancer Research and Clinical On… (2012)

  13. No Access

    Article

    A case of cervical multicentric Castleman disease treated with intensity-modulated radiation therapy using helical tomotherapy

    Castleman disease (CD) is a rare lymphoproliferative disorder. Two clinical entities are described: a unicentric form with disease confined to a single lymph node region and a multicentric form characterized b...

    Natsuo Tomita, Takeshi Kodaira, Takuya Tomoda in Japanese Journal of Radiology (2012)

  14. No Access

    Article

    Long-term follow-up and a detailed prognostic analysis of patients with oropharyngeal cancer treated with radiotherapy

    To find a prognostic factor for patients with oropharyngeal cancer (OPC) who were followed for long term after definitive radiotherapy.

    Natsuo Tomita, Takeshi Kodaira in Journal of Cancer Research and Clinical On… (2010)

  15. No Access

    Article

    Early salvage radiotherapy for patients with PSA relapse after radical prostatectomy

    To assess the effectiveness of early salvage radiotherapy (RT) for patients with prostate-specific antigen (PSA) relapse after radical prostatectomy (RP) retrospectively.

    Natsuo Tomita, Takeshi Kodaira in Journal of Cancer Research and Clinical On… (2009)

  16. Article

    Open Access

    Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results

    In stereotactic body radiotherapy (SBRT) for lung tumors, reducing tumor movement is necessary. In this study, we evaluated changes in tumor movement and percutaneous oxygen saturation (SpO2) levels, and prelimin...

    Fumiya Baba, Yuta Shibamoto, Natsuo Tomita, Chisa Ikeya-Hashizume in Radiation Oncology (2009)