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  1. Article

    Open Access

    Modified method of patency judgement using patency capsule prior to capsule endoscopy in clinical practice

    In 2012, Japan approved the use of a tag-less patency capsule (PC), which evaluates gastrointestinal patency before small-bowel capsule endoscopy (SBCE). This study aimed to evaluate the validity of our modifi...

    Takahiro Miyazu, Satoshi Osawa, Satoshi Tamura, Shinya Tani in Scientific Reports (2022)

  2. Article

    Open Access

    Lymphocyte to monocyte ratio and serum albumin changes predict tacrolimus therapy outcomes in patients with ulcerative colitis

    Tacrolimus therapy for ulcerative colitis is ineffective in certain patients; these patients require biologics or colectomy. We examined the ability of serum albumin levels and leukocyte subtypes to predict th...

    Natsuki Ishida, Shinya Tani, Yusuke Asai, Takahiro Miyazu in Scientific Reports (2022)

  3. Article

    Open Access

    Comparison between Prostaglandin E-major urinary metabolite and C-reactive protein levels to reflect endoscopic scores in patients with ulcerative colitis

    Prostaglandin E-major urinary metabolite (PGE-MUM) and C-reactive protein (CRP) are useful biomarkers in patients with ulcerative colitis. However, whether changes in endoscopic scores over time are reflected ...

    Natsuki Ishida, Satoshi Tamura, Takahiro Miyazu, Shinya Tani in Scientific Reports (2021)

  4. Article

    Open Access

    Prevalence of UL97 gene mutations and polymorphisms in cytomegalovirus infection in the colon associated with or without ulcerative colitis

    Cytomegalovirus (CMV) reactivation in the colon is common in patients with severe ulcerative colitis (UC). Ganciclovir (GCV) resistance conferring CMV UL97 gene mutations have been reported in recent years. Ho...

    Satoshi Tamura, Satoshi Osawa, Natsuki Ishida, Takahiro Miyazu in Scientific Reports (2021)

  5. Article

    Open Access

    C-reactive protein is superior to fecal biomarkers for evaluating colon-wide active inflammation in ulcerative colitis

    We evaluated the association between endoscopic scores of colonic inflammation and fecal calprotectin (FC), fecal immunochemical occult blood test (FIT), and C-reactive protein (CRP) in patients with ulcerativ...

    Natsuki Ishida, Tomohiro Higuchi, Takahiro Miyazu, Satoshi Tamura in Scientific Reports (2021)

  6. Article

    Open Access

    Mesalazine granule formulation improves clinical data in Crohn's disease compared with tablet formulation

    The efficacy of sustained-release preparations of mesalazine as a remission maintenance treatment for Crohn's disease remains to be established. We aimed to examine the changes in compliance rate and clinical ...

    Satoshi Tamura, Natsuki Ishida, Takahiro Miyazu, Shunya Onoue in Scientific Reports (2020)