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  1. Article

    Open Access

    In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water

    In vivo deuterated water (2H2O) labeling leads to deuterium (2H) incorporation into biomolecules of proliferating cells and provides the basis for its use in cell kinetics research. We hypothesized that rapidly p...

    Jeffrey R. Brender, Julian C. Assmann, Don E. Farthing, Keita Saito in Scientific Reports (2023)

  2. Article

    Open Access

    Comparing DNA enrichment of proliferating cells following administration of different stable isotopes of heavy water

    Deuterated water (2H2O) is a label commonly used for safe quantitative measurement of deuterium enrichment into DNA of proliferating cells. More recently, it has been used for labeling proteins and other biomolec...

    Don E. Farthing, Nataliya P. Buxbaum, Philip J. Lucas in Scientific Reports (2017)