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Article
Open AccessIn vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water
In vivo deuterated water (2H2O) labeling leads to deuterium (2H) incorporation into biomolecules of proliferating cells and provides the basis for its use in cell kinetics research. We hypothesized that rapidly p...
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Article
Open AccessComparing DNA enrichment of proliferating cells following administration of different stable isotopes of heavy water
Deuterated water (2H2O) is a label commonly used for safe quantitative measurement of deuterium enrichment into DNA of proliferating cells. More recently, it has been used for labeling proteins and other biomolec...