![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Clinical application of immune checkpoints in targeted immunotherapy of prostate cancer
Immunotherapy is considered as an effective method for cancer treatment owing to the induction of specific and long-lasting anti-cancer effects. Immunotherapeutic strategies have shown significant success in h...
-
Article
STAT3 inhibitory stattic enhances immunogenic cell death induced by chemotherapy in cancer cells
Induction of immunogenic cell death (ICD) is considered a promising strategy for cancer immunotherapy. Stattic is an inhibitor of STAT3, which is found constitutively active in many cancers and plays a major r...
-
Article
Open AccessTacrolimus ameliorates functional disturbances and oxidative stress in isoproterenol-induced myocardial infarction
The inflammatory responses play a major role in the pathogenesis of acute myocardial infarction (MI). Early inhibition of inflammation may improve post MI cardiac function. The aim of this study was to investi...
-
Article
Pioglitazone prevents morphine antinociception tolerance and withdrawal symptoms in rats
Long-term exposure to opiates induces tolerance to the analgesic effect and dependence. The purpose of the present study is to investigate the effects of pioglitazone, a peroxisome proliferator-activated recep...
-
Article
Open AccessPhytochemical screening and evaluation of cardioprotective activity of ethanolic extract of Ocimum basilicum L. (basil) against isoproterenol induced myocardial infarction in rats
The objectives of the present study were phytochemical screening and study of the effects of ethanolic extract of aerial parts of Ocimum basilicum (basil) on cardiac functions and histopathological changes in iso...
-
Article
Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats
It has been proposed that metformin exerts protective effects on ischemic hearts. In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters, and histopathological ...
-
Article
Open AccessProtective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats
The rhizomes of Cynodon dactylon are used for the treatment of heart failure in folk medicine. In the present study, we investigated the effects of hydroalcoholic extract of C. dactylon rhizomes on cardiac contra...
-
Article
Antinociceptive properties of extracts and two flavonoids isolated from leaves ofDanae racemosa
The antinociceptive properties of the hydro-methanolic extract (HME) and two flavonoids isolated fromDanae racemosa have been investigated in several nociceptive rat models. The HME fromD. racemosa (100-400 mgkg-...