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Article
Evaluation of two-dimensional total bone uptake (2D-TBU) and bone scan index (BSI) extracted from active bone metastatic burden on the bone scintigraphy in patients with radium-223 treatment
Radium-223 is a first alpha-emitting radionuclide treatment for metastatic castration-resistant prostate cancer (mCRPC) patients with bone metastases. Although the spread-based bone scan index (BSI) and novel ...
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Article
An approach for improvement of the accuracy of cancer gene panel testing
Tissue-based comprehensive genomic profiling (CGP) is increasingly being employed for genotype-directed therapies in patients with advanced cancer. However, tissue availability may limit their potential applic...
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Article
Open AccessIdentification of the growth cone as a probe and driver of neuronal migration in the injured brain
Axonal growth cones mediate axonal guidance and growth regulation. We show that migrating neurons in mice possess a growth cone at the tip of their leading process, similar to that of axons, in terms of the cy...
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Article
Open AccessReference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 edition
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia due to accelerated platelet destruction and impaired platelet production. Diagnosis of ITP is still ch...
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Article
Decision analysis of allogeneic bone marrow transplantation versus immunosuppressive therapy for young adult patients with aplastic anemia
Allogeneic bone marrow transplantation (BMT) from an HLA-matched sibling donor is recommended as an initial treatment for young patients. However, immunosuppressive therapy (IST) with cyclosporine and anti-thy...
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Article
Impact of patient body habitus on image quality and quantitative value in bone SPECT/CT
The first edition of guidelines for standardization of bone single photon emission computed tomography (SPECT) imaging was published in 2017, and the optimization and standardization are widely promoted. To th...
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Article
New standards for phantom image quality and SUV harmonization range for multicenter oncology PET studies
Not only visual interpretation for lesion detection, staging, and characterization, but also quantitative treatment response assessment are key roles for 18F-FDG PET in oncology. In multicenter oncology PET studi...
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Article
Open AccessImage quality and quantification accuracy dependence on patient body mass in 89Zr PET/CT imaging
This study was conducted to clarify how patient body mass affects the image quality and quantification accuracy of images obtained using 89Zr PET/CT. 89Zr PET/CT images from time-of-flight (TOF) PET/CT and semico...
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Article
Open AccessJapanese guideline for the oncology FDG-PET/CT data acquisition protocol: synopsis of Version 2.0
This synopsis outlines the Japanese guideline Version 2.0 for the data acquisition protocol of oncology FDG-PET/CT scans that was created by a joint task force of the Japanese Society of Nuclear Medicine Techn...
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Article
Standardization of image quality across multiple centers by optimization of acquisition and reconstruction parameters with interim FDG-PET/CT for evaluating diffuse large B cell lymphoma
A multicenter trial is currently underway using FDG-PET/CT to evaluate diffuse large B cell lymphoma in Japan (JSCT NHL10). Standardization of the image quality between the participating centers is a fundament...
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Article
Open AccessCombined effect of mitochondrial DNA 5178 C/A polymorphism and alcohol consumption on estimated glomerular filtration rate in male Japanese health check-up examinees: a cross-sectional study
Prevention of chronic kidney disease (CKD) is a major public health issue. Although several studies have been performed on the association between alcohol consumption and CKD or renal function, it remains cont...
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Article
Open AccessMitochondrial DNA 5178 C/A polymorphism influences the effects of habitual smoking on the risk of dyslipidemia in middle-aged Japanese men
Several genetic polymorphisms have been reported to modify the effects of smoking on serum lipid levels. The objective of this study was to investigate whether longevity-associated mitochondrial DNA 5178 (Mt51...
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Article
Open AccessJoint effect of longevity-associated mitochondrial DNA 5178 C/A polymorphism and alcohol consumption on risk of hyper-LDL cholesterolemia in middle-aged Japanese men
Combined effects between mitochondrial DNA 5178 (Mt5178) C/A polymorphism and alcohol consumption on the risk of hypertension or hyperuricemia have been reported. The objective of this study was to investigate...
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Article
Fragment c gamma receptor gene polymorphisms and breast cancer risk in case–control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
Previous studies showing the presence of antibodies against tumor-associated antigens in healthy individuals suggest that antibody-dependent cell cytotoxicity (ADCC) might play a role in the development of bre...
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Article
Open AccessRelationship of body mass index to percent body fat and waist circumference among schoolchildren in Japan - the influence of gender and obesity: a population-based cross-sectional study
Although the correlation coefficient between body mass index (BMI) and percent body fat (%BF) or waist circumference (WC) has been reported, studies conducted among population-based schoolchildren to date have...
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Article
Evaluation of the risk of radiation exposure from new 18FDG PET/CT plans versus conventional X-ray plans in patients with pediatric cancers
Unnecessary radiological examination should be avoided, particularly for children, who are more vulnerable to radiation than adults. Replacement of X-ray examination with 18F-fluoro-2-deoxy-d-glucose (18FDG) posi...
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Article
Multi-bed-position acquisition technique for deep inspiration breath-hold PET/CT: a preliminary result for pulmonary lesions
The deep inspiration breath-hold (DIBH) technique for positron emission tomography/computed tomography (PET/CT) is under investigation for its contribution to the accurate diagnosis of pulmonary lesions. “Step...
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Chapter and Conference Paper
Tuberculosis among the poor
Several studies have been conducted to investigate the effectiveness of tuberculosis (TB) control programs among the poor. These include 1) Research on TB among the poor and 2) A survey regarding the use of gr...
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Article
Association of thoracic kyphosis with subjective poor health, functional activity and blood pressure in the community-dwelling elderly
The prevalence of thoracic kyphosis is considered to increase as the population is ageing in Japan. However, little is known about the clinical and preventive significance of kyphosis. The purpose of the study...
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Article
Formation of TiO2 nanotubes by thermal decomposition of poly(vinyl alcohol)-titanium alkoxide hybrid nanofibers
Anatase type TiO2 nanotubes were formed by calcination of poly(vinyl alcohol)-Ti alkoxide hybrid precursor nanofibers in air. The outer and inner diameters of the TiO2 nanotubes calcined at 500 °C for 5 h were ca...
