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Open AccessThe effect of education regarding treatment guidelines for schizophrenia and major depressive disorders on psychiatrists' hypnotic medication prescribing behavior: a multicenter study
To examine whether the "Effectiveness of Guideline for Dissemination and Education in psychiatric treatment (EGIUDE)" project affects the rate of prescriptions of hypnotic medication and the type of hypnotic m...
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Article
Open AccessSubcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using the current diagnostic system based on presenting symptoms and signs. The creation of a novel diagnostic syste...
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Open AccessCerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals
According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder (ASD) are classified bas...
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Open AccessChange of prescription for patients with schizophrenia or major depressive disorder during admission: real-world prescribing surveys from the effectiveness of guidelines for dissemination and education psychiatric treatment project
Polypharmacy of additional psychotropics alongside the main treatment drug (antipsychotics in schizophrenia and antidepressants in major depressive disorder) is common in Japan. Our goal is to align psychotrop...
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Open AccessThe characteristics of discharge prescriptions including pro re nata psychotropic medications for patients with schizophrenia and major depressive disorder from the survey of the “Effectiveness of guidelines for dissemination and education in psychiatric treatment (EGUIDE)” project
Several guidelines recommend monotherapy in pharmacotherapy for schizophrenia and major depressive disorder. The content of regular prescriptions has been reported in several studies, but not enough research h...
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Article
Activated partial thromboplastin time-based clot waveform analysis enables measurement of very low levels of factor IX activity in patients with severe hemophilia B
The precise measurement of very low levels of factor IX activity (FIX:C < 1 IU/dL) is essential for understanding clinical severity and risk of inhibitor development in patients with severe hemophilia B (Pw-SH...
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Article
Open AccessHydrogen spillover-driven synthesis of high-entropy alloy nanoparticles as a robust catalyst for CO2 hydrogenation
High-entropy alloys (HEAs) have been intensively pursued as potentially advanced materials because of their exceptional properties. However, the facile fabrication of nanometer-sized HEAs over conventional cat...
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Open AccessComprehensive assessment of left atrial and ventricular remodeling in paroxysmal atrial fibrillation by the cardiovascular magnetic resonance myocardial extracellular volume fraction and feature tracking strain
Atrial fibrillation (AF) is a progressive disease that starts with structural or functional changes in the left atrium and left ventricle, and evolves from paroxysmal toward sustained forms. Early detection of...
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Article
Radiometric compensation for non-rigid surfaces by continuously estimating inter-pixel correspondence
In recent years, radiometric compensation techniques for realizing ideal image projection, even for a patterned surface, have attracted attention. In radiometric compensation, the influence of the pattern can ...
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Article
Differences in fractional anisotropy between the patients with schizophrenia and healthy comparison subjects
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Open AccessWhite matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals
Identifying both the commonalities and differences in brain structures among psychiatric disorders is important for understanding the pathophysiology. Recently, the ENIGMA-Schizophrenia DTI Working Group perfo...
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Article
A study of IoT malware activities using association rule learning for darknet sensor data
Along with the proliferation of Internet of Things (IoT) devices, cyberattacks towards these devices are on the rise. In this paper, we present a study on applying Association Rule Learning to discover the reg...
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Open AccessAdditional chemotherapy improved local control and overall survival after stereotactic body radiation therapy for patients with oligo-recurrence
Oligo-recurrence has been considered to confer improved prognosis than other oligometastatic conditions, and stereotactic body radiation therapy (SBRT) is considered as an option of local therapy for lung or l...
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Article
Expansion of TALE homeobox genes and the evolution of spiralian development
Spiralians, including molluscs, annelids and platyhelminths, share a unique development process that includes the typical geometry of early cleavage and early segregation of cell fate in blastomeres along the ...
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Open AccessAtypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis
Atypical femoral fracture (AFF) occurs with minor trauma in patients receiving antiresorptive drugs such as bisphosphonate and denosumab. We hypothesized that patients with bone metastasis who receive higher d...
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Open AccessErratum to: Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
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Open AccessCarbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
Desmoid tumors, which are associated with familial adenomatous polyposis (FAP), tend to occur frequently in the abdominal wall and mesentery. Currently, there are no recognized treatments other than surgery, a...
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Open AccessLong-term efficacy and tolerability of quetiapine in patients with schizophrenia who switched from other antipsychotics because of inadequate therapeutic response—a prospective open-label study
While the frequency and importance of antipsychotic switching in patients with schizophrenia, there is insufficient evidence with regard to switching strategy. Quetiapine is one of the drugs of choice for swit...
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The value of 4-month neurocognitive function as an endpoint in brain metastases trials
To investigate whether the neurocognitive function at 4 months could be a relevant primary endpoint in clinical trials dealing with brain metastases, we created a Japanese neurocognitive battery and examined t...
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Open AccessComputed tomographic lymphography for sentinel lymph node biopsy in male breast cancer: report of two cases
Male breast cancer is rare, accounting for less than 1% of breast cancers. Because of its rarity evidence of the usefulness sentinel lymph node biopsy (SLNB) for male breast cancer has not been established. Mo...
