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Article
Urease-producing bacteria combined with pig manure biochar immobilize Cd and inhibit the absorption of Cd in lettuce (Lactuca sativa L.)
The synergistic remediation of heavy metal-contaminated soil by functional strains and biochar has been widely studied. However, the mechanisms by which urease-producing bacteria combine with pig manure biocha...
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Article
Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1
Cytokinins are essential for plant growth and development, and their tissue distributions are regulated by transmembrane transport. Recent studies have revealed that members of the ‘Aza-Guanine Resistant’ (AZG...
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Article
Open AccessLigand activation mechanisms of human KCNQ2 channel
The human voltage-gated potassium channel KCNQ2/KCNQ3 carries the neuronal M-current, which helps to stabilize the membrane potential. KCNQ2 can be activated by analgesics and antiepileptic drugs but their act...
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Article
Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands
The transient receptor potential vanilloid 2 (TRPV2) ion channel is a polymodal receptor widely involved in many physiological and pathological processes. Despite many TRPV2 modulators being identified, whethe...
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Article
Publisher Correction: Structures and mechanisms of the Arabidopsis auxin transporter PIN3
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Article
Structures and mechanisms of the Arabidopsis auxin transporter PIN3
The PIN-FORMED (PIN) protein family of auxin transporters mediates polar auxin transport and has crucial roles in plant growth and development1,2. Here we present cryo-electron microscopy structures of PIN3 from
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Article
Open AccessCrystal structure of the INTS3/INTS6 complex reveals the functional importance of INTS3 dimerization in DSB repair
SOSS1 is a single-stranded DNA (ssDNA)-binding protein complex that plays a critical role in double-strand DNA break (DSB) repair. SOSS1 consists of three subunits: INTS3, SOSSC, and hSSB1, with INTS3 serving ...
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Article
Open AccessDevelo** a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps
Hydroxytyrosol is an antioxidant free radical scavenger that is biosynthesized from tyrosine. In metabolic engineering efforts, the use of the mouse tyrosine hydroxylase limits its production. Here, we design ...
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Article
Open AccessStructural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases
Pif1 plays multiple roles in maintaining genome stability and preferentially unwinds forked dsDNA, but the mechanism by which Pif1 unwinds forked dsDNA remains elusive. Here we report the structure of Bacteroides...
