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  1. No Access

    Article

    New insights into the role of the immune inhibitory receptor VSTM1 in autoimmune disease

    Naijun Miao, **g Wang in Cellular & Molecular Immunology (2024)

  2. Article

    Open Access

    Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus

    Although extracellular DNA is known to form immune complexes (ICs) with autoantibodies in systemic lupus erythematosus (SLE), the mechanisms leading to the release of DNA from cells remain poorly characterized...

    Naijun Miao, Zhuning Wang, Qinlan Wang, Hongyan **e, Ninghao Yang… in Nature Communications (2023)

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  3. Article

    Open Access

    Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still’s disease pathogenesis

    Hyperferritinemic syndrome, an overwhelming inflammatory condition, is characterized by high ferritin levels, systemic inflammation and multi-organ dysfunction, but the pathogenic role of ferritin remains larg...

    **chao Jia, Mengyan Wang, Jianfen Meng, Yuning Ma, Yang Wang… in Nature Communications (2022)

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  4. Article

    Open Access

    RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice

    Progressive tubulointerstitial fibrosis is the common final outcome for all kidney diseases evolving into chronic kidney disease (CKD), whereas molecular mechanisms driving fibrogenesis remain elusive. Retinoi...

    Zhuanli Zhou, Jiayun Ni, **gyao Li, Chuanbing Huo… in Journal of Molecular Medicine (2020)

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