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  1. Article

    Open Access

    Increased exposure to acute thermal stress is associated with a non-linear increase in recombination frequency and an independent linear decrease in fitness in Drosophila

    Meiotic recombination rate has long been known to be phenotypically plastic. How plastic recombination evolves and is maintained remains controversial; though a leading model for the evolution of plastic recom...

    Savannah Jackson, Dahlia M. Nielsen, Nadia D. Singh in BMC Evolutionary Biology (2015)

  2. No Access

    Article

    Estimation of Fine-Scale Recombination Intensity Variation in the white–echinus Interval of D. melanogaster

    Accurate assessment of local recombination rate variation is crucial for understanding the recombination process and for determining the impact of natural selection on linked sites. In Drosophila, local recomb...

    Nadia D. Singh, Charles F. Aquadro, Andrew G. Clark in Journal of Molecular Evolution (2009)

  3. Article

    Open Access

    Similar Levels of X-linked and Autosomal Nucleotide Variation in African and non-African populations of Drosophila melanogaster

    Levels of molecular diversity in Drosophila have repeatedly been shown to be higher in ancestral, African populations than in derived, non-African populations. This pattern holds for both coding and noncoding ...

    Nadia D Singh, J Michael Macpherson, Jeffrey D Jensen in BMC Evolutionary Biology (2007)

  4. Article

    Open Access

    Minor shift in background substitutional patterns in the Drosophila saltans and willistoni lineages is insufficient to explain GC content of coding sequences

    Several lines of evidence suggest that codon usage in the Drosophila saltans and D. willistoni lineages has shifted towards a less frequent use of GC-ending codons. Introns in these lineages show a parallel shift...

    Nadia D Singh, Peter F Arndt, Dmitri A Petrov in BMC Biology (2006)

  5. No Access

    Article

    Codon Bias and Noncoding GC Content Correlate Negatively with Recombination Rate on the Drosophila X Chromosome

    The patterns and processes of molecular evolution may differ between the X chromosome and the autosomes in Drosophila melanogaster. This may in part be due to differences in the effective population size between ...

    Nadia D. Singh, Jerel C. Davis, Dmitri A. Petrov in Journal of Molecular Evolution (2005)