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Open AccessSARS-CoV-2 antigenemia and RNAemia in association with disease severity in patients with COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, causes a spectrum of symptoms ranging from mild upper to severe lower respiratory tract infections. However, the d...
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Open AccessClinically differential diagnosis of human granulocytic anaplasmosis and severe fever with thrombocytopenia syndrome
This study analyzed HGA and SFTS in patients with suspected tick-borne infection by focusing on key differences that clinicians can easily recognize. A retrospective analysis was performed on confirmed patient...
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Article
Open AccessWhole-genome analysis and mutation pattern of SARS-CoV-2 during first and second wave outbreak in Gwangju, Republic of Korea
To investigate the specific genomic features and mutation pattern, whole and near-complete SARS-CoV-2 genome sequences were analyzed. Clinical samples were collected from 18 COVID-19–positive patients and subj...
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Open AccessCorrection to: Molecular detection and identification of Culex flavivirus in mosquito species from Jeju, Republic of Korea
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Open AccessComparison of RT-PCR, RT-nested PCRs, and real-time PCR for diagnosis of severe fever with thrombocytopenia syndrome: a prospective study
We designed a highly sensitive reverse transcription nested polymerase chain reaction targeting the M-segment (NPCR-M) of severe fever with thrombocytopenia syndrome (SFTS) virus. NPCR-M was performed in paral...
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Open AccessMolecular detection and identification of Culex flavivirus in mosquito species from Jeju, Republic of Korea
Mosquito-borne flaviviruses are prime pathogens and have been a major hazard to humans and animals. They comprise several arthropod-borne viruses, including dengue virus, yellow fever virus, Japanese encephali...
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Open AccessClinical usefulness of 16S ribosomal RNA real-time PCR for the diagnosis of scrub typhus
Scrub typhus is a major acute febrile disease in the Asia–Pacific region. The purpose of the present study is to investigate the clinical usefulness of real-time PCR (Q-PCR) of 16S rRNA for the diagnosis of sc...
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Article
Open AccessHuman granulocytic anaplasmosis in a Single University Hospital in the Republic of Korea
To date, only a few studies have analyzed the clinical characteristics and genetic features of human granulocytic anaplasmosis (HGA) in South Korea. Thus, in this study, we investigated the clinical characteri...
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Open AccessFirst report of the molecular detection of human pathogen Rickettsia raoultii in ticks from the Republic of Korea
Rickettsial diseases associated with the spotted fever group constitute a growing number of newly identified Rickettsia pathogens and their tick vectors in various parts of the world. At least 15 distinct tick sp...
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Open AccessFollow-up investigation of antibody titers and diagnostic antibody cutoff values in patients with scrub typhus in South Korea
Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. Few follow-up studies have assessed antibody titers using serologic tests from various commercial laboratories and the Korea Cente...
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Open AccessA case of SFTS coinfected with E. coli bacteremia
Severe fever thrombocytopenia syndrome virus (SFTSV) is the causative agent of severe fever thrombocytopenia syndrome (SFTS). SFTS is an emerging infectious disease, characterized by high fever, gastrointestin...
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Open AccessFirst identification of Anaplasma phagocytophilum in both a biting tick Ixodes nipponensis and a patient in Korea: a case report
Human granulocytic anaplasmosis (HGA) is a tick-borne infectious disease caused by Anaplasma phagocytophilum. To date, there have been no reported cases of A. phagocytophilum infection found in both the biting ti...
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Open AccessAsymptomatic-anaplasmosis confirmation using genetic and serological tests and possible coinfection with spotted fever group Rickettsia: a case report
Anaplasmosis is an emerging acute febrile disease that is caused by a bite of an Anaplasma phagocytophilum–infected hard tick. As for healthy patients, reports on asymptomatic anaplasmosis resulting from such tic...
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Open AccessScalp eschar and neck lymphadenopathy after tick bite (SENLAT) caused by Bartonella henselae in Korea: a case report
Tick-borne lymphadenopathy (TIBOLA) is an infectious disease, mainly caused by species from the spotted fever group rickettsiae and is characterized by enlarged lymph nodes following a tick bite. Among cases o...
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Molecular detection of viruses causing hemorrhagic fevers in rodents in the south-west of Korea
Many pathogens causing hemorrhagic fevers of medical and veterinary importance have been identified and isolated from rodents in the Republic of Korea (ROK). We investigated the occurrence of emerging viruses ...
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Open AccessIndicators of severe prognosis of scrub typhus: prognostic factors of scrub typhus severity
Scrub typhus is an acute disease, characterized by symptoms of fever, which occurs due to infection by Orientia tsutsugamushi. In most cases, patients recover from the disease with appropriate treatment, but seri...
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Open AccessIdentifying the mechanism underlying treatment failure for Salmonella Paratyphi A infection using next-generation sequencing – a case report
Salmonella is a notorious pathogen that causes gastroenteritis in humans and the emergence of resistance to third-generation cephalosporins and azithromycin have raised concern. There has been rare case of Salmon...
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Open AccessManifestation of anaplasmosis as cerebral infarction: a case report
Human granulocytic anaplasmosis is a tick-borne zoonotic disease caused by Anaplasma phagocytophilum, an obligate intracellular granulocytotropic bacterium.
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Open AccessTenosynovitis caused by Scedosporium apiospermum infection misdiagnosed as an Alternaria species: a case report
Scedosporium apiospermum, which can usually be isolated from soil, polluted stream water and decaying vegetation, is increasingly recognized as an opportunistic dematiaceous fungus. Th...
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Open AccessThe clinical characteristics of pleural effusion in scrub typhus
The aim of this study is to identify the factors associated with the occurrence of pleural effusion and to investigate the characteristics of pleural effusion in scrub typhus.
