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Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells
Alternative splicing of pre-mRNA increases proteomic diversity, a crucial mechanism in defining tissue identity. We demonstrate differentially spliced interleukin (IL)-7 in distinct anatomic areas in the adult...
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Article
Mass spectrometrical analysis of human serine racemase in foetal brain
We analysed human serine racemase for the first time from human foetal brain by mass spectrometrical methods, MALDI MS and MS/MS. The detection of human serine racemase from a transient area of human foetal br...
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Article
Die vaginale Hysterektomie
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Book
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Striatum
The striatum is composed of two distinct compartments: the patch compartment (striosomes) and matrix. Patches have been shown to be neurochemically different from the matrix (Graybiel et al. 1981; Graybiel 199...
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Basal Nucleus of Meynert
Enlargement of the telencephalic cortex during phylogenesis is associated with an analogous development of subcortical nuclei, which provide extrathalamic afferents to the cerebral cortex. One of these nuclei ...
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Red Nucleus
The red nucleus located in the tegmentum of the mesencephalon is connected with the cerebral cortex, the cerebellum, brain stem nuclei, and the spinal cord. In the primate red nucleus, two subdivisions can be ...
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Introduction
In the mature brain, calcium ions play pivotal roles in transmembrane and intracellular transmission of signals. Thus, calcium is involved in numerous neuronal functions including neurotransmitter release, enz...
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Cerebral Cortex: Cortical Plate
The layers of the cerebral cortex are generated in an orderly sequence. The precursor cells of the deepest layers leave the proliferative zone to migrate first to the cortical plate. Thus, the laminar position...
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Ganglionic Eminence
Within the neuroepithelium lining, the ventricle proliferation of neuronal and glial precursor cells takes place. In particular during the early and middle period of fetal development, a circumscribed enlargem...
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Amygdala
The amygdaloid complex is localized in the depth of the temporal lobe. It consists of a series of nuclei, each of which displays distinct cyto- and chemoarchitectural and connectional characteristics (Amaral e...
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Hypothalamic Tuberomamillary Nucleus
The hypothalamic nuclei occupy inferior portions of the diencephalon below the hypothalamic sulcus. The hypothalamus extends from the lamina terminalis to a vertical plane posterior to the mamillary bodies, an...
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Thalamic Reticular Complex
The thalamic reticular nucleus is a sheet of neurons which enfolds the dorsal thalamus laterally. It lies between the external medullary lamina and the internal capsule. The superior and inferior poles of the ...
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Summary
Recent studies have demonstrated that antibodies against the calcium-binding proteins (CaBPs) parvalbumin (PV), calbindin (CB), and calretinin (CR) are appropriate tools for demonstrating transient features an...
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Cerebral Cortex: Subplate
The first cortical neurons separate from the proliferative zone (i.e., ventricular zone) and build up a single layer on the nonventricular side called primitive plexiforme layer or preplate. Then a third zone ...
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Cerebral Cortex: Molecular Layer (Layer I)
The molecular layer can be subdivided into two portions: the upper portion (layer Ia) contains large neurons called Cajal-Retzius cells; in the lower portion (layer Ib) horizontally oriented fibers are present...
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Article
Immunmodulation am unreifen fetalen Gehirn
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Article
Differential expression of calcium-binding proteins in the red nucleus of the develo** and adult human brain
The adult human red nucleus consists of two parts: (1) the parvocellular part, which is clearly separated from (2) the magnocellular part. The latter and its rubrospinal projection is known to be rudimentary i...
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Transiente Charakteristika des fetalen Gehirns und ihre Bedeutung für ZNS-Komplikationen des Frühgeborenen
Zu Beginn der Entwicklung des Zentralnervensystems (ZNS) wird die Wand des Neuralrohrs von einem mehrreihigen Neuroepithel gebildet, das eine hohe Proliferationsaktivität zeigt. Zunächst enthält das in der Fol...
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Article
Monoclonal antibodies SMI 311 and SMI 312 as tools to investigate the maturation of nerve cells and axonal patterns in human fetal brain
Neurofilaments, which are exclusively found in nerve cells, are one of the earliest recognizable features of the maturing nervous system. The differential distribution of neurofilament proteins in varying degr...
