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  1. No Access

    Article

    Evaluation of systemic targeting of RET oncogene-based MTC with tumor-selective peptide-tagged Ad vectors in clinical mouse models

    Significant advantage of targeted antitumoral treatment consists in the possibility to restrict maximum therapeutic efficacy to the malignant cell population by reducing toxicity in healthy tissues. Using diff...

    A Schmidt, C Eipel, K Fürst, N Sommer, J Pahnke, B M Pützer in Gene Therapy (2011)

  2. No Access

    Article

    The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

    In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) the cytokines tumour necrosis factor-α (TNF), lymphotoxin-α (LT), and interferon-gamma (IFN-γ) are of central pat...

    N. Sommer, P.-A. Löschmann, G.H. Northoff, M. Weller, A. Steinbrecher… in Nature Medicine (1995)