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Article
Open AccessEnabling magnetic pulse welding for dissimilar tubular arrester cable joints
Climate change exacerbates the need for resource-efficient and cost-effective production processes across manifold industries, including the field of electrical connections. This specific field is characterize...
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Article
Open AccessHigh-Strength Dissimilar Welds Between a NiTi Shape Memory Alloy and Titanium Obtained by Intermixing Niobium Using Pulsed Laser Beam Welding
Joining of NiTi shape memory alloys with commercially pure titanium (Ti) is of great interest for manifold industrial applications. However, dissimilar fusion welding of these materials is associated with the ...
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Article
Open AccessElectron Beam Welding of Hot-Rolled Fe–Mn–Al–Ni Shape Memory Alloy Sheets
The present study focuses on the weldability of hot-rolled Fe–Mn–Al–Ni shape memory alloy sheets by vacuum electron beam welding. Tailored process-specific welding parameters, such as preheating with electron ...
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Article
Open AccessGrain growth and precipitation behaviour of AISI 430 ferritic stainless steel subjected to pulsed laser beam welding using free-form pulse sha**
Ferritic stainless steels are prone to grain coarsening and precipitation of chromium-rich grain boundary phases during fusion welding, which increase intergranular corrosion susceptibility. State-of-the-art t...
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Article
Ambulant erworbene Pneumonie
Die ambulant erworbene Pneumonie („community aquired pneumonia“, CAP) ist eine häufige und potenziell tödliche Erkrankung. Vor dem Hintergrund einer hohen Letalität innerhalb der ersten Tage ist bei klinischem...
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Article
Lungenembolie
Die Lungenembolie (LE) tritt relativ häufig und als potenziell tödliche Erkrankung in der Intensiv- und Notfallmedizin auf. Vor dem Hintergrund einer besonders hohen Letalität innerhalb der ersten Stunden nach...
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Article
Lungenembolie
Die Lungenembolie (LE) tritt relativ häufig und als potenziell tödliche Erkrankung in der Intensiv- und Notfallmedizin auf. Vor dem Hintergrund einer besonders hohen Letalität innerhalb der ersten Stunden nach...
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Article
Medikamentöse Therapie der pulmonalen Hypertonie
Die pulmonale Hypertonie (PH) ist eine chronisch progrediente Erkrankung der pulmonalen Zirkulation multifaktorieller Ursache. Die aktuelle diagnostische Klassifikation der PH unterscheidet fünf Hauptgruppen, ...
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Article
The novel orally active guanylhydrazone CPSI-2364 prevents postoperative ileus in mice independently of anti-inflammatory vagus nerve signaling
Postoperative ileus (POI) is an iatrogenic complication of abdominal surgery, mediated by a severe inflammation of the muscularis externa (ME). Previously, we demonstrated that intravenous application of the t...
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Article
Evaluation of systemic targeting of RET oncogene-based MTC with tumor-selective peptide-tagged Ad vectors in clinical mouse models
Significant advantage of targeted antitumoral treatment consists in the possibility to restrict maximum therapeutic efficacy to the malignant cell population by reducing toxicity in healthy tissues. Using diff...
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Chapter and Conference Paper
Die orale Gabe von CPSI 2364 verhindert den postoperativen Ileus im Großtiermodell ohne Beeinflussung der intestinalen Wundheilung
Background. The mechanical trauma of the gut is an unavoidable consequence of abdominal surgery leading to postoperative ileus (POI). Former studies revealed that activation of resident m...
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Chapter and Conference Paper
Preoperative application of CPSI 2364 per os prevents postoperative ileus in rodents and swine
The mechanical trauma of the gut is an unavoidable consequence of abdominal surgery leading to massive inflammation of the entire bowel wall and subsequently in postoperative ileus [1]. Further studies revealed t...
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Chapter and Conference Paper
Simultaneous Measurement of Local Cortical Blood Flow and Tissue Oxygen Saturation by Near Infra-Red Laser Doppler Flowmetry and Remission Spectroscopy in the Pig Brain
In the current study we evaluated the combined use of Near-infrared Laser-Doppler flowmetry (NiLDF) and Remission Spectroscopy (RS) for measurement of regional perfusion and oxygen saturation of the cerebral c...
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Article
Treatment of arterial hypertension with diuretics, beta- and calcium channel blockers in old patients
Hypertension increases in prevalence with age. Population based studies suggest that more than 50% of people over the age of 65 years may have chronic hypertension.¶ Hypertension, especially systolic hypert...
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Chapter
Perkutane endoskopische Gastrostomie/PEG in der Geriatrie
Bei der perkutanen endoskopischen (kontrollierten) Gastrostomie/PEG handelt es sich um ein Verfahren zur enteralen Ernährung und Flüssigkeitszufuhr unter Umgehung des zervikothorakalen Verdauungstraktes. Diese...
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Article
Multiple Sklerose Neue therapeutische Strategien im experimentellen Stadium
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Article
The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis
In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) the cytokines tumour necrosis factor-α (TNF), lymphotoxin-α (LT), and interferon-gamma (IFN-γ) are of central pat...
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Chapter
Astrophotography
Compared with direct visual observing, photography has the distinct advantage, owing to the light-integrating properties of the photographic emulsion, of being able to record the images of faint objects not wi...
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Chapter and Conference Paper
Neurosarkoidose: Neuere diagnostische Möglichkeiten und Falldarstellung
Neurologische Komplikationen treten bei 5 % der Patienten mit Sarkoidose auf. In etwa 50% dieser Betroffenen stellen die neurologischen Ausfälle die Erstsymptome der Erkrankung dar. Die Diagnose einer primären...
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Chapter and Conference Paper
Liquor- und Serumfibronektin bei entzündlichen und neo-plastischen Erkrankungen des Zentralnervensystems
Fibronektine wurden 1978 erstmals im Liquor nachgewiesen (3) und 1989 als prognostischer Parameter im Liquor bei der akuten lymphatischen Leukämie eingeführt (6). Die Bedeutung des physiologischen Liquorfibron...