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    Heptylphysostigmine — Novel Acetylcholinesterase Inhibitor: Biochemical and Behavioral Pharmacology

    The discovery in the 1970’s that choline acetyltransferase (ChAT) is markedly reduced in the brains of patients with Alzheimer’s disease (AD) compared with those of age-matched controls (Bowen et al., 1976) pr...

    L. L. Iversen, G. Bentley, G. Dawson… in Cholinergic Basis for Alzheimer Therapy (1991)