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Article
Study of the Photoprotector Activity of Melanin Gel in an Ultraviolet Erythema Model in Rats
Results from a study of the photoprotective effect of a melanin-based gel using an ultraviolet erythema model in rats are presented. Use of gels containing melanin, melanin and menthol, and Africa Kids photopr...
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Article
Isolation of Polysaccharides from Horse Chestnut (Aesculus hippocastanum L.) Shells and their Acute Toxicity and Influence on the Immune System
The acute toxicity and influence on the immune system of the melanin–polysaccharide complex and β-glucans isolated from horse chestnut shells (Aesculus hippocastanum L.) were studied. The β-glucans were obtained ...
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Article
Experimental Study of Local Anesthetic Activity and Acute Toxicity of a Combined Gel
Results from studies of the local anesthetic activity of a gel for surface anesthesia that was developed at A. S. Sadykov Institute of Bioorganic Chemistry of the Academy of Sciences of the Republic of Uzbekis...
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Article
Fludigel Composition Development and its Anti-Inflammatory and Anti-Allergic Properties
A technology for treatment of allergies complicated by fungal infection was developed based on Fludigel composition comprising a complex of therapeutic agents including the immunomodulating drug Thymoptin, the...
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Article
Preparation and Physicochemical and Biological Properties of Molecular Associates of Lagochilin and Lagochirsine with Glycyrrhizic Acid and its Monoammonium Salt
Molecular associates of lagochilin and lagochirsine with glycyrrhizic acid and its monoammonium salt in various molar ratios were prepared. Their IR spectra, several physicochemical properties, and hemostatic ...
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Article
Synthesis, structures, and acute toxicity of gossypol nonsymmetrical aldehyde derivatives
Nonsymmetrical aldehyde derivatives of gossypol, a yellow polyphenolic pigment of cottonseed, were synthesized by reactions with ammonia, aniline, 4-aminoantipyrine, and barbituric acid. Their structures were ...
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Article
Synthesis and biological activity of N-benzyl derivatives of cytisine
The reductive alkylation of cytisine by various aromatic aldehydes was studied. Preliminary pharmacological investigations of the synthesized compounds were performed.
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Article
Structure-Activity Relationship for Hemostatic Lagochilin Diterpenoids
The structure-hemostatic activity relationship of lagochilin and its natural and synthetic derivatives was investigated.