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Chapter and Conference Paper
Brain tissue biomechanics in cortical contusion injury: a finite element analysis
The controlled cortical impact model has been used extensively to study focal traumatic brain injury. Although the impact variables can be well defined, little is known about the biomechanical trauma as delive...
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Chapter and Conference Paper
Communicating Hydrocephalus: The Biomechanics of Progressive Ventricular Enlargement Revisited
This article investigates the physical mechanisms involved in the chronic ventricular enlargement that accompanies communicating hydrocephalus (CH) — including its normal and low-pressure forms. In particular,...
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Article
Ventricle shunting in young H-Tx rats with inherited congenital hydrocephalus: a quantitative histological study of cortical grey matter
Shunt surgery is the usual treatment for infantile hydrocephalus, but its precise effects on ventricles and cortex are not well understood. Infant H-Tx rats with inherited hydrocephalus, which have progressive...
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Article
CO2 cerebrovascular reactivity as a function of perfusion pressure — a modelling study
A mathematical model is described that demonstrated the properties of cerebral vascular resistance and compliance expressed as a function of cerebral perfusion pressure (CPP) and arterial CO2 partial pressure (Pa...
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Article
The cerebral cortex in congenital hydrocephalus in the H-Tx rat: a quantitative light microscopy study
Hydrocephalus in the H-Tx rat first develops in late gestation and causes death at 4–7 weeks. The effect of hydrocephalus on overall cortical dimensions and on five specific regions (frontal, sensory-motor, pa...