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Article
Drosophila melanogaster as a model for studying protein-encoding genes that are resident in constitutive heterochromatin
The organization of chromosomes into euchromatin and heterochromatin is one of the most enigmatic aspects of genome evolution. For a long time, heterochromatin was considered to be a genomic wasteland, incompa...
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La chirurgia mininvasiva per i tumori solidi dell’infanzia
La chirurgia mininvasiva, che comprende la laparoscopia, la retroperitoneoscopia e la toracoscopia, è diventata, nel corso degli ultimi due decenni, un mezzo sicuro e affidabile per ridurre l’onere della chiru...
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Article
Adolescents et cancer: une prise en charge spécifique pour ne plus être lost in transition
The population of adolescents and young adults (AYA) in France has derived little benefit from the advances in oncology in recent decades. Nevertheless, the number of epidemiological studies and publications i...
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Article
Improvement of overall survival after allogeneic hematopoietic stem cell transplantation for children and adolescents: a three-decade experience of a single institution
Allogeneic stem cell transplantation (allo-SCT) has become an essential component of the treatment for a variety of diseases in pediatric patients. During the past decades, advances in the transplant technolog...
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Article
Évolution de la prise en charge des sarcomes de l’enfant et de l’adolescent
Les sarcomes de l’enfant et l’adolescent sont des pathologies rares, comprenant des sarcomes des parties molles de type « pédiatrique » ou « adulte » et des sarcomes osseux. Ces tumeurs sont généralement chimi...
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Article
Open AccessLow expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways
Rhabdomyosarcoma (RMS) is the most frequent form of pediatric soft-tissue sarcoma. It is divided into two main subtypes: ERMS (embryonal) and ARMS (alveolar). Current treatments are based on chemotherapy, surg...
