-
Chapter and Conference Paper
Development of GaN HEMTs Based Biosensor
In this paper, we report on the development of GaN HEMTs for sensing/biosensing applications. Various process steps are optimized at each stages for the development of device. Device shows the 0.5 A/mm drain c...
-
Chapter and Conference Paper
AlGaN/GaN HEMT Based pH Sensor
The sensitivity of GaN HEMTs upon exposure of the gate area to phosphate buffer solution (PBS) has been explored. Output drain characteristic of the device reveals that the drain current decreases linearly wit...
-
Article
Association of diet and lifestyle with glycated haemoglobin in type 1 diabetes participants in the EURODIAB prospective complications study
Diet and lifestyle advice for type 1 diabetes (T1DM) patients is based on little evidence and putative effects on glycaemic control. Therefore, we investigated the longitudinal relation between dietary and lif...
-
Article
Open AccessP10.11 Mean Arterial Pressure is a Stronger Predictor of Stroke in South Asian Than European Men, Independent of Other Cardiometabolic Risk Factors; The Sabre Study
Stroke risk is greater in South Asians than Europeans. We sought to compare associations between blood pressure (BP) and stroke by ethnicity and determine how BP contributes to ethnic differences in disease.
-
Article
P3.13: Associations of Central and Peripheral Pulse Pressure with Heart Structure, Systolic and Diastolic Function in Adolescence: Findings From a General Population Cohort
In adults central blood pressure has stronger associations with cardiovascular outcomes than peripheral blood pressure, with some evidence that this difference is greater in mid- than older-aged adults. The re...
-
Article
P4.24: Dietary Inorganic Nitrate Lowers Central Blood Pressure
Dietary inorganic nitrate is reduced to (nitric oxide) NO in the body. Beetroot is a rich source of dietary inorganic nitrate and has been shown to lower brachial blood pressure (BP) by this mechanism. The eff...
-
Article
2.1: Ethnic Differences in Associations Between Carotid Imt, Coronary Artery Calcification and Cerebrovascular Disease. a Population-Based Study of Europeans, South Asians and African Caribbeans
We compared associations between common carotid intima-media thickness(IMT)) and coronary artery calcification(CAC)) and measures of cerebrovascular disease (CVD) in 3 ethnic groups.
-
Article
3.3: Total Arterial Elastance is More Strongly Associated with Cardiovascular Disease Than Carotid-Femoral Pulse Wave Velocity
Arterial stiffness is associated with an increased risk of cardiovascular disease (CVD) and carotid-femoral pulse wave velocity (cfPWV) is considered as the ‘gold standard’ measurement method. However cfPWV do...
-
Article
Theoretical study of nematogenic behaviour of para-hexyl-p′-cyanobiphenyl
Intermolecular interactions between a pair of para-hexyl-p′-cyanobiphenyl (6CB) molecules have been evaluated using modified second order perturbation treatment along with multicentred-multipole expansion meth...
-
Article
Association of physical activity with all-cause mortality and incident and prevalent cardiovascular disease among patients with type 1 diabetes: the EURODIAB Prospective Complications Study
The aim of this study was to examine the association of physical activity (PA) with all-cause mortality and incident and prevalent cardiovascular disease (CVD) among patients with type 1 diabetes.
-
Article
Open AccessP1.13 Ethnic Differences in Wave Intensity and Arterial Stiffness in the Carotid Artery
In comparison with Europeans (E) in the UK, Indian Asian (IA) people have a 1.5 to 2-fold elevated risk of cardiovascular disease (CVD), and the risk of stroke is more than 2-fold higher in African Caribbean (...
-
Article
Open AccessP1.12 Ethnic Differences in Left Ventricle Myocardial Oxygen Demand
There are marked inter-ethnic differences in coronary heart disease (CHD). Indian Asians (IA) have 50% greater and African Caribbeans (AC) 50% less CHD than white Europeans (E) in the UK. Reasons for this are ...
-
Article
Open AccessDietary saturated fat and fibre and risk of cardiovascular disease and all-cause mortality among type 1 diabetic patients: the EURODIAB Prospective Complications Study
Low adherence to recommendations for dietary saturated fatty acid (SFA) and fibre intake in patients with type 1 diabetes mellitus may heighten their increased risk of cardiovascular disease (CVD) and mortalit...
-
Article
Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis
Multiple genetic variants are associated with type 2 diabetes-related traits in Europeans, but their role in South Asian populations needs further study. We hypothesised that genetic variants associated with d...
-
Article
Open AccessP7.03: Subclinical Measures of Atherosclerosis Associate Differently with Prevalent Coronary Heart Disease in Indian Asians and Europeans
Globally Indian Asians have increased risk of coronary heart disease (CHD). Subclinical markers of atherosclerosis, such as carotid intima media thickness (CIMT) and coronary artery calcification scores (CACS)...
-
Article
Exposure to candesartan during the first trimester of pregnancy in type 1 diabetes: experience from the placebo-controlled diabetic retinopathy candesartan trials
The teratogenic consequences of angiotensin-converting enzyme inhibitors angiotensin receptor blockers (ARBs) during the second and third trimesters of pregnancy are well described. However, the consequences o...
-
Article
Open AccessP8.08 A Method Comparison of Central Blood Pressure Measurements by Pulsecor and Sphygmocor Devices
Estimated aortic (or central) systolic pressure (cSBP) differs from peripheral pressure and may be a better predictor of cardiovascular events. SphygmoCor® (AtCor, Sydney, Australia) uses applanation tonometer...
-
Article
Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease
A high prevalence of diabetes contributes to excess CHD in Indian Asians, but the underlying mechanisms are unclear. Heart rate, heart rate variability (HRV) and baroreflex sensitivity (BRS) are measures of ca...
-
Article
Persistence of TNFα in diabetic wounds
-
Article
Open AccessProgression to microalbuminuria in type 1 diabetes: development and validation of a prediction rule
Microalbuminuria is common in type 1 diabetes and is associated with an increased risk of renal and cardiovascular disease. We aimed to develop and validate a clinical prediction rule that estimates the absolu...
