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  1. No Access

    Article

    C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation

    Overexpression of the BRE (brain and reproductive organ-expressed) gene defines a distinct pediatric and adult acute myeloid leukemia (AML) subgroup. Here we identify a promoter enriched for active chromatin mark...

    A E Marneth, K H M Prange, A S A Al Hinai, S M Bergevoet, N Tesi… in Leukemia (2018)

  2. Article

    Open Access

    Androgen metabolism in prostate cancer: from molecular mechanisms to clinical consequences

    Despite our most vigorous efforts, prostate cancer remains the second leading cause of cancer death in men. Understanding the intricacies of androgen metabolism is vital to finding therapeutic targets, particu...

    K-H Chang, C E Ercole, N Sharifi in British Journal of Cancer (2014)

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  3. No Access

    Article

    The role of DAB2IP in androgen receptor activation during prostate cancer progression

    Altered androgen-receptor (AR) expression and/or constitutively active AR are commonly associated with prostate cancer (PCa) progression. Targeting AR remains a focal point for designing new strategy of PCa th...

    K Wu, J Liu, S-F Tseng, C Gore, Z Ning, N Sharifi, L Fazli, M Gleave, P Kapur… in Oncogene (2014)