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Article
The effects of new life-prolonging drugs for metastatic castration-resistant prostate cancer (mCRPC) patients in a real-world population
In 2004 docetaxel was the first life-prolonging drug (LPD) registered for metastatic castration-resistant prostate cancer (mCRPC) patients. Between 2011 and 2014 new LPDs for mCRPC (cabazitaxel, abiraterone, e...
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Article
Open Access68Ga-PSMA-PET/CT and Diffusion MRI Targeting for Cone-Beam CT-Guided Bone Biopsies of Castration-Resistant Prostate Cancer Patients
Precision medicine expands the treatment options for metastatic castration-resistant prostate cancer (mCRPC) by targeting druggable genetic aberrations. Aberrations can be identified following molecular analys...
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Article
The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs
The large-scale genetic profiling of tumours can identify potentially actionable molecular variants for which approved anticancer drugs are available1–3. However, when patients with such variants are treated with...
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Article
Open AccessNatriuretic peptide-induced hyponatremia in a patient with left atrial myxoma
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Article
Long-term outcome of undifferentiated spondylarthropathy
Undifferentiated spondylarthropathy is one of the common disease subsets in the group of so-called seronegative spondarthritides. It is not exactly known how often it differentiates into ankylosing spondylitis...
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Article
Preparation and characterization of Ag-added Bi1.84Pb0.4Sr2Ca2.2Cu3O10+x bulk tube conductors for cryogen free superconducting magnet
Bulk tube conductors of Bi 1.84 Pb 0.4 Sr ...
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Article
Effects of social change on well-being: Boom and bust in a Western Canadian city
Drawing from surveys done over a eight year period, we find some important effects on well-being coming from economic boom and bust in a Western Canadian city. This effect is buffered, however, by the importan...