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The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53–p21 axis

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  1. Article

    Open Access

    Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells

    Cancer cells are characterized by the Warburg effect, a shift from mitochondrial respiration to oxidative glycolysis. We report here the crucial role of cyclin D1 in promoting this effect in a cyclin-dependent...

    M. Caillot, J. Bourgeais, H. Dakik, É. Costé, N. M. Mazure, É. Lelièvre… in Oncogenesis (2020)

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  2. Article

    miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

    Following the identification of a set of hypoxia-regulated microRNAs (miRNAs), recent studies have highlighted the importance of miR-210 and of its transcriptional regulation by the transcription factor hypoxi...

    M-P Puisségur, N M Mazure, T Bertero, L Pradelli, S Grosso… in Cell Death & Differentiation (2011)

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