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  1. Article

    Open Access

    Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells

    Current differentiation protocols for generating mesencephalic dopaminergic (mesDA) neurons from human pluripotent stem cells result in grafts containing only a small proportion of mesDA neurons when transplan...

    Muyesier Maimaitili, Muwan Chen, Fabia Febbraro, Ekin Ucuncu… in Nature Communications (2023)

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  2. No Access

    Protocol

    Generation of Human iPSCs by Episomal Reprogramming of Skin Fibroblasts and Peripheral Blood Mononuclear Cells

    Human-induced pluripotent stem cells (iPSCs) can be generated from patient-specific somatic cells by forced expression of the transcription factors OCT4, SOX2, KLF4, and c-MYC. Sustained expression of the tran...

    Fabia Febbraro, Muwan Chen, Mark Denham in Nuclear Reprogramming (2021)

  3. No Access

    Article

    Interference in the endplate nutritional pathway causes intervertebral disc degeneration in an immature porcine model

    Previous studies have shown that blocking the endplate nutritional pathway with bone cement did not result in obvious intervertebral disc degeneration (IDD) in mature animal models. However, there are very few...

    Ran Kang, Haisheng Li, Steffen Ringgaard, Kresten Rickers… in International Orthopaedics (2014)

  4. Article

    Open Access

    A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds

    We describe a simple method for bone engineering using biodegradable scaffolds with mesenchymal stem cells derived from human induced-pluripotent stem cells (hiPS-MSCs). The hiPS-MSCs expressed mesenchymal mar...

    Li** Zou, Yonglun Luo, Muwan Chen, Gang Wang, Ming Ding… in Scientific Reports (2013)

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