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  1. Article

    Open Access

    Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy

    This study aims to clarify the immunogenicity in acquired and innate immune responses of cultured human corneal endothelial cells (hCECs) applied for cell injection therapy, a newly established modality for co...

    Munetoyo Toda, Morio Ueno, Jun Yamada, Asako Hiraga, Kazuko Asada in Scientific Reports (2022)

  2. No Access

    Article

    A physical biomarker of the quality of cultured corneal endothelial cells and of the long-term prognosis of corneal restoration in patients

    Dysfunction of the corneal endothelium reduces the transparency of the cornea and can cause blindness. Because corneal endothelial cells have an extremely limited proliferative ability in vivo, treatment for c...

    Akihisa Yamamoto, Hiroshi Tanaka, Munetoyo Toda in Nature Biomedical Engineering (2019)

  3. Article

    Open Access

    Distinct Aqueous Humour Cytokine Profiles of Patients with Pachychoroid Neovasculopathy and Neovascular Age-related Macular Degeneration

    This study investigated the pathophysiological features of pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) by analysing and comparing cytokine profiles in aqueous hum...

    Nobuhiro Terao, Hideki Koizumi, Kentaro Kojima, Tetsuya Yamagishi in Scientific Reports (2018)