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  1. No Access

    Chapter

    Orally Active DACH-Pt (IV) Compounds

    Since the discovery of the antitumor activity of cisplatin by Rosenberg, et al.1 in 1969, many attempts have been made to prepare highly antitumor active Pt complexes without severe toxicities. The authors discov...

    Yoshinori Kidani, Ryoichi Kizu… in Platinum and Other Metal Coordination Comp… (1996)

  2. No Access

    Article

    Chromatographic Simulation of the Effect of a Polyvalent Counter Ion on Retention Behavior and Peak Intensity of Sulfate

    The effect of a mobile phase polyvalent counter ion on the retention behavior and peak intensity of sulfate in non-suppressed ion chromatography was quantitatively studied using a chromatogram simulation metho...

    Masayuki Nishimura, Morimasa Hayashi, Atsushi Yamamoto… in Analytical Sciences (1994)

  3. No Access

    Article

    Ion Chromatographic Study of Sulfate-Triethylenetetramine Complexes in Aqueous Solution

    The selective effect of triethylenetetramine (Trien) on the retention behavior of sulfate in ion chromatography was studied. When Trien was added to an eluant as a counter ion, retention of sulfate was selecti...

    Masayuki Nishimura, Morimasa Hayashi, Kazuichi Hayakawa… in Analytical Sciences (1994)

  4. No Access

    Article

    Flow Injection Analysis for Trace Aluminum with On-Line Preconcentration and Spectrophotometric Detection

    We developed a flow injection analysis method for the determination of trace aluminum in water coupled with on-line preconcentration on salicylideneamino-2-thiophenol immobilized glass beads (SAB) and spectrop...

    Jun Kobayashi, Miyako Baba, Motoichi Miyazaki in Analytical Sciences (1994)

  5. No Access

    Article

    Pharmacokinetics of (1R,2R-diaminocyclohexane)oxalatoplatinum(II) in comparison with cisplatin following a single intravenous injection in rabbits

    The pharmacokinetics of (1R,2R-diaminocyclohexane)oxalatoplatinum(II) (1-OHP, NSC-266046), a second-generation antitumor platinum complex, was studied in rabbits and compared with that of cisplatin. The rabbits w...

    Ryoichi Kizu, Shin-ichi Higashi, Yoshinori Kidani… in Cancer Chemotherapy and Pharmacology (1993)

  6. No Access

    Article

    Preconcentration/Ion Chromatography with Indirect Photometric Detection for Anions

    Kazuichi Hayakawa, Jun Kobayashi, Mikako Ohmori, Mayumi Ohya… in Analytical Sciences (1993)

  7. No Access

    Article

    High-Performance Liquid Chromatography of Iproplatin, an Antitumor Quadrivalent Platinum Complex

    Iproplatin [cis-dichloro-trans-dihydroxo-bis(isopropylamine)platinum(IV), CHIP] is a potent antitumor platinum complex with axial hydroxy ligands. The high-performance liquid chromatographic behavior of CHIP was ...

    Ryoichi Kizu, Manabu Kaneda, Motoichi Miyazaki in Analytical Sciences (1992)

  8. No Access

    Article

    Selective Peak Enhancement and Suppression in Conductometric Ion Chromatography and Its Application to the Determination of Trace Levels of Orthophosphate in Environmental Samples

    In non-suppressed conductometric ion chromatography, when a carboxylic acid eluent of low pH is used, the signal intensity (ΔHC) is proportional to the sum of the conductivity change caused by changes in the samp...

    Kazuichi Hayakawa, Akio Kato, Atsushi Yamamoto, Motoichi Miyazaki in Analytical Sciences (1992)

  9. No Access

    Article

    On-Line Removal of Interfering Alkaline Earth Metals for Simultaneous Determination of Hydrogen Carbonate, Chloride, Nitrate and Sulfate by Indirect Photometric Detection Ion Chromatography

    Kazuichi Hayakawa, Kyoko Nomura, Motoichi Miyazaki in Analytical Sciences (1991)

  10. No Access

    Article

    Polarized Photometric Detector for High-Performance Liquid Chromatography

    A photometric detector for an optically active compound is described in which two polarizers are set on both sides of the flow cell. When a nonchromophoric, optically active compound passes through the cell, t...

    Atsushi Yamamoto, Akinobu Matsunaga, Kazuichi Hayakawa… in Analytical Sciences (1991)

  11. No Access

    Article

    Determination of Diamino- and Aminopyrenes by High Performance Liquid Chromatography with Chemiluminescence Detection

    A high performance liquid chromatographic (HPLC) method with chemiluminescence (CL) detection was developed for the sensitive determination of 1,3-diaminopyrene (1,3-DAP), 1,6-DAP, 1,8-DAP and 1-aminopyrene (1...

    Kazuichi Hayakawa, Ryuichi Kitamura, Mizuka Butoh, Noriko Imaizumi… in Analytical Sciences (1991)

  12. No Access

    Article

    Determination of Malic Acid Enantiomers by Ligand-Exchange Photometric Ion Chromatography

    Atsushi Yamamoto, Kazuichi Hayakawa, Akinobu Matsunaga… in Analytical Sciences (1991)

  13. No Access

    Article

    Determination of Carboxylesters by Indirect Photometric Ion Chromatography with an On-Line Enzyme Immobilized Column

    Carboxylesters, carboxylic and inorganic anions were determined separately by photometric ion chromatography with an enzyme immobilized column. In the system, a carboxylesterase immobilized column (4.6 mm i.d....

    Kazuichi Hayakawa, Seiji Nakamura, Kotoe Inaki, Motoichi Miyazaki in Analytical Sciences (1989)