17 Result(s)

Article

Chest computed tomography with multiplanar reformatted images for diagnosing traumatic bronchial rupture: a case report

Unnoticed bronchial injury during the early stage of resuscitation of multiple trauma is not rare and increases mortality and morbidity.

Morgan Le Guen, Catherine Beigelman, Belaid Bouhemad, Yang Wenjïe… in Critical Care (2007)

Article

Extracorporeal life support following out-of-hospital refractory cardiac arrest

Extracorporeal life support (ECLS) has recently shown encouraging results in the resuscitation of in-hospital (IH) refractory cardiac arrest. We assessed the use of ECLS following out-of-hospital (OH) refracto...

Morgan Le Guen, Armelle Nicolas-Robin, Serge Carreira, Mathieu Raux… in Critical Care (2011)

Article

Airway response to acute mechanical stress in a human bronchial model of stretch

Lung inflation may have deleterious effects on the alveoli during mechanical ventilation. However, the consequences of stretch during excessive lung inflation on basal tone and responsiveness of human bronchi ...

Christophe Faisy, Francisco M Pinto, Morgan Le Guen, Emmanuel Naline… in Critical Care (2011)

Article

Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial

To compare automated administration of propofol and remifentanil guided by the Bispectral index (BIS) versus manual administration of short-acting drugs in critical care patients requiring deep sedation. The p...

Morgan Le Guen, Ngai Liu, Eric Bourgeois, Thierry Chazot… in Intensive Care Medicine (2013)

Article

Cardiorespiratory effects of recruitment maneuvers and positive end expiratory pressure in an experimental context of acute lung injury and pulmonary hypertension

Recruitment maneuvers (RM) and positive end expiratory pressure (PEEP) are the cornerstone of the open lung strategy during ventilation, particularly during acute lung injury (ALI). However, these intervention...

Camille Doras, Morgan Le Guen, Ferenc Peták, Walid Habre in BMC Pulmonary Medicine (2015)

Article

New Fast-Track Concepts in Thoracic Surgery: Anesthetic Implications

Fast-track anesthesia has become the standard of care for many surgical procedures, especially for colectomy. Its practice in cardiac surgery has been extensive mainly for economic reasons. On the other hand, ...

Morgan Le Guen, Bernard Cholley, Marc Fischler in Current Anesthesiology Reports (2016)

Article

The impact of low-frequency, low-force cyclic stretching of human bronchi on airway responsiveness

In vivo, the airways are constantly subjected to oscillatory strain (due to tidal breathing during spontaneous respiration) and (in the event of mechanical ventilation) positive pressure. This exposure is espe...

Morgan Le Guen, Stanislas Grassin-Delyle, Emmanuel Naline… in Respiratory Research (2016)

Article

Frailty Related to Anesthesia guided by the Index “bispectraL” (FRAIL) study: study protocol for a randomized controlled trial

Currently, patients older than 60 years of age represent 25% of the population and are at an increased risk during surgery. Therefore, reducing postoperative morbidity and mortality is a major concern in medic...

Morgan Le Guen, Marie Herr, Antoine Bizard, Caroline Bichon, Nathalie Boichut… in Trials (2017)

Article

Multimodal prehabilitation in colorectal cancer patients to improve functional capacity and reduce postoperative complications: the first international randomized controlled trial for multimodal prehabilitation

Colorectal cancer (CRC) is the second most prevalent type of cancer in the world. Surgery is the only curative option. However, postoperative complications occur in up to 50% of patients and are associated wit...

Stefanus van Rooijen, Francesco Carli, Susanne Dalton, Gwendolyn Thomas… in BMC Cancer (2019)

Article

Clinical characterization of dysautonomia in long COVID-19 patients

Increasing numbers of COVID-19 patients, continue to experience symptoms months after recovering from mild cases of COVID-19. Amongst these symptoms, several are related to neurological manifestations, includi...

Nicolas Barizien, Morgan Le Guen, Stéphanie Russel, Pauline Touche… in Scientific Reports (2021)

Article

One small wearable, one giant leap for patient safety?

Frederic Michard, Robert H. Thiele… in Journal of Clinical Monitoring and Computi… (2022)

Article

Characteristics and outcomes of patients undergoing anesthesia while SARS-CoV-2 infected or suspected: a multicenter register of consecutive patients

There are limited data to detail the perioperative anesthetic management and the incidence of postoperative respiratory complications among patients requiring an anesthetic procedure while being SARS-CoV-2 pos...

Arthur James, Audrey De Jong, Thomas Jeanmougin, Antonia Blanie… in BMC Anesthesiology (2022)

Article

Effect of an individualized versus standard blood pressure management during mechanical thrombectomy for anterior ischemic stroke: the DETERMINE randomized controlled trial

Hypotension and blood pressure (BP) variability during endovascular therapy (EVT) for acute ischemic stroke (AIS) due to an anterior large vessel occlusion (LVO) is associated with worse outcomes. However, the...

Benjamin Maïer, Benjamin Gory, Russell Chabanne, Benoît Tavernier… in Trials (2022)

Article

Goal-Directed Fluid Therapy and major postoperative complications in elective craniotomy. A retrospective analysis of a before-after multicentric study

Goal-Directed Fluid Therapy (GDFT) is recommended to decrease major postoperative complications. However, data are lacking in intra-cranial neurosurgery.

Morgan Le Guen, Amandine Le Gall-Salaun, Julien Josserand… in BMC Anesthesiology (2023)