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    Article

    Activation of diverse signalling pathways by oncogenic PIK3CA mutations

    The PIK3CA gene is frequently mutated in human cancers. Here we carry out a SILAC-based quantitative phosphoproteomic analysis using isogenic knockin cell lines containing ‘driver’ oncogenic mutations of PIK3CA t...

    **nyan Wu, Santosh Renuse, Nandini A. Sahasrabuddhe in Nature Communications (2014)

  2. Article

    Open Access

    The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation

    Although a high frequency of androgen receptor (AR) expression in human breast cancers has been described, exploiting this knowledge for therapy has been challenging. This is in part because androgens can eith...

    Joseph P Garay, Bedri Karakas, Abde M Abukhdeir, David P Cosgrove in Breast Cancer Research (2012)

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    Article

    Controversial BRCA1 allelotypes in commonly used breast cancer cell lines

    Sivasundaram Karnan, Morassa Mohseni, Yuko Konishi in Breast Cancer Research and Treatment (2010)