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  1. No Access

    Article

    A surgical orthotopic approach for studying the invasive progression of human bladder cancer

    The invasion of bladder cancer into the sub-urothelial muscle and vasculature are key determinants leading to lethal metastatic progression. However, the molecular basis is poorly understood, partly because of...

    Guadalupe Lorenzatti Hiles, Angelica L. Cates, Layla El-Sawy in Nature Protocols (2019)

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    Open Access

    Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer

    Members of the human epidermal growth factor receptor (HER) family play a significant role in bladder cancer progression and may underlie the development of chemotherapy resistance. Dacomitinib is an irreversi...

    Petros D. Grivas, Kathleen C. Day, Andreas Karatsinides, Alyssa Paul in Molecular Medicine (2013)

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    Article

    Extravesical cryosurgical approach for VX2 bladder tumor in rabbits

    This study characterized the VX2 bladder cancer model in rabbits and tested the feasibility of treating bladder cancer by extravesical cryosurgery. After the growth characteristics of the VX2 bladder tumor mo...

    Wen-Horng Yang, Monica Liebert, Roger E. Price, Douglas M. Cromeens in Urological Research (2001)

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    Article

    MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells

    The development and progression of bladder cancer is associated with multiple alterations in the genome, including loss of chromosome 10. Recently, MMAC1/PTEN, a phosphatidylinositol phosphatase, has been mapped ...

    Motoyoshi Tanaka, Dimpy Koul, Michael A Davies, Monica Liebert, Peter A Steck in Oncogene (2000)

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    Chapter

    Urothelial Differentiation and Bladder Cancer

    Cancer is the endpoint of a multi-step process of carcinogenesis.1–5 This process involves multiple genetic and epigenetic alterations and cellular selections.2–4,6 These changes result in cell populations with u...

    Monica Liebert, Daniel Gebhardt, Christopher Wood in Advances in Bladder Research (1999)

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    Article

    The intraperitoneal delivery of radiolabeled monoclonal antibodies: studies on the regional delivery advantage

    The i.p. delivery of murine monoclonal antibody was compared with i.v. delivery in normal mice and rats, in normal nude mice and in those with i.p. human ovarian carcinoma xenografts. In normal rats, all class...

    Richard L. Wahl, Jeffrey Barrett, Onelio Geatti in Cancer Immunology, Immunotherapy (1988)

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    Article

    High-dose, unlabeled, nonspecific antibody pretreatment: influence on specific antibody localization to human melanoma xenografts

    Nonspecific uptake of radiolabeled monoclonal antibodies in normal tissues is a significant problem for tumor imaging. A potential means of decreasing nonspecific antibody binding is to “blockade” nonspecific ...

    Richard L. Wahl, Barry S. Wilson, Monica Liebert in Cancer Immunology, Immunotherapy (1987)

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    Article

    CML characterization of a product of a second class I locus in the rat MHC

    In the rat, genes that control the expression of target antigens detected by cell-mediated lympholysis (CML) are present in the major histocompatibility complex (MHC). The relationship of these loci, CT and Ag-L,...

    Monica Liebert, Heinz W. Kunz, Thomas J. Gill III, Donald V. Cramer in Immunogenetics (1982)

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    Article

    Gene order in the major histocompatibility complex of the rat

    The loci in the major histocompatibility complex (MHC) of the rat which code for class I and class II antigens—RT1.A and RT1.B, respectively — have previously been separated by laboratory-derived recombinants and...

    Heinz W. Kunz, Thomas J. Gill III, Monica Liebert, Stephen M. Katz in Immunogenetics (1981)