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Article
Open AccessIdentification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment
Pancreatic cancer is one of the most difficult cancers to detect early and most patients die from complications arising due to distant organ metastases. The lack of bona fide early biomarkers is one of the pri...
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Article
Open AccessNF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1
H. pylori infection is the main risk factor for gastric cancer. In this study, we investigated H. pylori-mediated activation of STAT3 and NF-κB in gastric cancer, using in vitro and in vivo models.
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Article
Albuminuria correlates with hemolysis and NAG and KIM-1 in patients with sickle cell anemia
Although hyperfiltration and albuminuria are common pathological conditions, kidney injury (KI) biomarkers have been seldom studied in individuals with sickle cell anemia (SCA).
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Article
Atherosclerosis within the non-neoplastic margin of partial nephrectomy specimens: implications for medical management
To describe the frequency and severity of atherosclerosis contained within the non-neoplastic tissue of partial nephrectomy (PN) specimens.
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Article
Pathologic evaluation of non-neoplastic renal parenchyma in partial nephrectomy specimens
This study aimed to identify non-neoplastic pathologic changes in partial nephrectomy specimens of patients without a known history of medical comorbidities. Routine analysis of this tissue may allow the clini...
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Article
Open AccessSystemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature
Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case repor...