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  1. Article

    Open Access

    Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma

    Liposarcomas (LPSs) are a group of malignant mesenchymal tumors showing adipocytic differentiation. Here, to gain insight into the enhancer dysregulation and transcriptional addiction in this disease, we chart...

    Ye Chen, Liang Xu, Anand Mayakonda, Mo-Li Huang, Deepika Kanojia in Nature Communications (2019)

  2. Article

    Open Access

    Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression

    Squamous cell carcinomas (SCCs) are aggressive malignancies. Previous report demonstrated that master transcription factors (TFs) TP63 and SOX2 exhibited overlap** genomic occupancy in SCCs. However, functio...

    Yuan Jiang, Yan-Yi Jiang, Jian-Jun **e, Anand Mayakonda in Nature Communications (2018)

  3. No Access

    Article

    Molecular analysis of early rice stamen development using organ-specific gene expression profiling

    Elucidating the regulatory mechanisms of plant organ formation is an important component of plant developmental biology and will be useful for crop improvement applications. Plant organ formation, or organogen...

    **ao-Chun Lu, Hua-Qin Gong, Mo-Li Huang, Su-Lan Bai, Yang-Bo He in Plant Molecular Biology (2006)