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Article
Open AccessBromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma
Liposarcomas (LPSs) are a group of malignant mesenchymal tumors showing adipocytic differentiation. Here, to gain insight into the enhancer dysregulation and transcriptional addiction in this disease, we chart...
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Article
Open AccessCo-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression
Squamous cell carcinomas (SCCs) are aggressive malignancies. Previous report demonstrated that master transcription factors (TFs) TP63 and SOX2 exhibited overlap** genomic occupancy in SCCs. However, functio...
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Article
Molecular analysis of early rice stamen development using organ-specific gene expression profiling
Elucidating the regulatory mechanisms of plant organ formation is an important component of plant developmental biology and will be useful for crop improvement applications. Plant organ formation, or organogen...