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Article
Open AccessAutomated exploitation of the big configuration space of large adsorbates on transition metals reveals chemistry feasibility
Mechanistic understanding of large molecule conversion and the discovery of suitable heterogeneous catalysts have been lagging due to the combinatorial inventory of intermediates and the inability of humans to...
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Article
Open AccessSPIN90, an adaptor protein, alters the proximity between Rab5 and Gapex5 and facilitates Rab5 activation during EGF endocytosis
During ligand-mediated receptor endocytosis, the small GTPase Rab5 functions in vesicle fusion and trafficking. Rab5 activation is known to require interactions with its guanine nucleotide-exchange factors (GE...
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Article
Open AccessMassive single visit cervical pre-cancer and cancer screening in eastern Democratic Republic of Congo
In the Democratic Republic of Congo (DRC), practical and affordable strategies for cervical cancer screening are needed to detect and treat pre-cancerous and cancerous lesions in a timely fashion. This study p...
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Chapter and Conference Paper
How Accurate Is Brain Volumetry?
We evaluate the accuracy and precision of different techniques for measuring brain volumes based on MRI. We compare two established software packages that offer an automated image analysis, EMS and SIENAX, and...
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Chapter and Conference Paper
Mast Cells in Atherogenesis: A Model for Studying Proteolytic Modification of Low and High Density Lipoproteins
Immunohistochemical observations on human atherosclerotic lesions have revealed that the lesions contain, not only foam cells, but also mast cells. Studies taking advantage of in vitro and in vivo models that use...
