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Article
Targeting cathepsin L in the regulation of apoptosis in peripheral T-cell lymphoma
Peripheral T-cell lymphoma (PTCL) is a heterogeneous lymphoproliferative neoplasms derived from post-thymic T lymphocytes and mature NK cells. Although the incidence is rare, PTCL is frequently recurrence with...
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Article
Open AccessSFXN3 is a Prognostic Marker and Promotes the Growth of Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease with rapid progression and frequent mutations. Sideroflexin3 (SFXN3) has been shown to be involved in various neurodegenerative diseases. However, the ro...
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Article
Open AccessApplication of flipped classroom combined with virtual simulation platform in clinical biochemistry practical course
The study explores an innovative teaching mode that integrates Icourse, DingTalk, and online experimental simulation platforms to provide online theoretical and experimental resources for clinical biochemistry...
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Article
Open AccessVenetoclax and Azacitidine in Chinese patients with untreated acute myeloid leukemia ineligible for intensive chemotherapy
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Article
Exogenous salicylic acid enhanced resistance of Foxtail Millet (Setaria italica) to Sclerospora graminicola
To ward off pathogens, plants establish innate immunity system in which salicylic acid (SA) plays an important role. The downy mildew of foxtail millet (Setaria italica) is an oomycete disease caused by biotrophi...
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Article
Open AccessHaploidentical vs matched sibling donor transplant for paroxysmal nocturnal haemoglobinuria: A multicenter study
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Article
LMP1-specific cytotoxic T cells for the treatment of EBV-related post-transplantation lymphoproliferative disorders
Epstein–Barr virus-specific cytotoxic T lymphocytes (EBV-CTLs) represent a promising treatment option for EBV-associated post-transplantation lymphoproliferative disorders (PTLD). However, production of EBV-CT...
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Article
Retrospective analysis of 769 cases of sudden cardiac death from 2006 to 2015: a forensic experience in China
Sudden cardiac death (SCD) is a major health challenge. The records of 769 autopsy cases of SCD examined at Tongji Medicolegal Expertise Center from January 2006 to December 2015 were retrospectively reviewed....
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Article
Open AccessDownregulation of ATG5-dependent macroautophagy by chaperone-mediated autophagy promotes breast cancer cell metastasis
Recent data have shown that the expression of lysosome-associated membrane protein type 2 A (LAMP2A), the key protein in the chaperone-mediated autophagy (CMA) pathway, is elevated in breast tumor tissues. How...
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Article
Open AccessInterferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells
Our previous work demonstrated that ectopic expression of interferon regulatory factor 4 binding protein (IBP) was correlated with the malignant behaviour of human breast cancer cells. The mechanisms controlli...
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Article
Application of a Fab fragment of monoclonal antibody specific to N-terminal pro-brain natriuretic peptide for the detection based on regeneration-free electrochemical immunosensor
N-Terminal pro-brain natriuretic peptide (NT-proBNP) is an important marker for heart failure that reflects ventricular volume expansion, ventricular overload and the degree of cardiac in...
