-
Article
Open AccessEffect of different application duration of a venous foot pump on prevention of venous thromboembolism after hip and knee arthroplasty: a multicenter prospective clinical trial
To investigate the optimal duration of applying a venous foot pump (VFP) in the prevention of venous thromboembolism (VTE) following hip and knee arthroplasty.
-
Article
Open AccessEpidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Tissue patterning is critical for the development and regeneration of organs. To advance the use of engineered reconstituted skin organs, we study cardinal features important for tissue patterning and hair reg...
-
Article
Hair Zinc and Chromium Levels Were Associated with a Reduced Likelihood of Age Related Cognitive Decline in Centenarians and Oldest-Old Adults
Cognitive function has inevitable decline with advancing age in nature, and age-related cognitive decline (ARCD) is of increasing concern to aging population. Scarce study has involved the associations between...
-
Article
Open AccessStability and biosafety of human epidermal stem cell for wound repair: preclinical evaluation
Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), the efficacy, biosafety and quality control of EpiSC th...
-
Article
Open AccessA novel nomogram to stratify quality of life among advanced cancer patients with spinal metastatic disease after examining demographics, dietary habits, therapeutic interventions, and mental health status
It would be very helpful to stratify patients and direct patient selection if risk factors for quality of life were identified in a particular population. Nonetheless, it is still challenging to forecast the h...
-
Article
Open AccessA prediction model for worsening diabetic retinopathy after panretinal photocoagulation
As one of the severe complications of diabetes mellitus, diabetic retinopathy (DR) is the leading cause of blindness in the working age worldwide. Although panretinal photocoagulation (PRP) was standard treatm...
-
Article
Open AccessCharacteristics of clinical trials related to hip fractures and factors associated with completion
This study aimed at investigating the characteristics of clinical trials related to hip fractures that were registered at ClinicalTrials.gov. It also aimed to identify potential risk factors associated with co...
-
Article
Open AccessA novel model to predict mental distress among medical graduate students in China
Poor mental health was reported among medical graduate students in some studies. Identification of risk factors for predicting the mental health is capable of reducing psychological distress among medical grad...
-
Article
Open AccessPrediction of early vascular cement leakage following percutaneous vertebroplasty in spine metastases: the Peking University First Hospital Score (PUFHS)
Cement leakage into venous blood posed significant challenge to surgeons. The aim of the study was to create a Peking University First Hospital Score (PUFHS) which could evaluate the probability of vascular ce...
-
Reference Work Entry In depth
Evo-Devo of Scales, Feathers, and Hairs
Integument forms the interface between the organism and its environment. Because of the need for adaptation, it has evolved a robust ability to regenerate under physiological conditions (age, sex, and season) ...
-
Reference Work Entry In depth
Hair Follicle Stem Cells and Hair Regeneration
The hair follicle (HF), forming embryonically through cutaneous epithelial-mesenchymal interaction, is a sophisticated multifunctional organ. In addition to its protective, thermoregulatory, mechanosensory, an...
-
Living Reference Work Entry In depth
Hair Follicle Stem Cells and Hair Regeneration
The hair follicle (HF), forming embryonically through cutaneous epithelial-mesenchymal interaction, is a sophisticated multifunctional organ. In addition to its protective, thermoregulatory, mechanosensory, an...
-
Living Reference Work Entry In depth
Evo-Devo of Scales, Feathers, and Hairs
Integument forms the interface between the organism and its environment. Because of the need for adaptation, it has evolved a robust ability to regenerate under physiological conditions (age, sex, and season) ...
-
Article
Open AccessNFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium
How high-salt intake leads to the occurrence of many cardiovascular diseases such as atherosclerosis is a fundamental question in pathology. Here we postulated that high-salt-induced NFAT5 controls the inflamm...
-
Article
Open AccessEffect of reduction quality on post-operative outcomes in 31-A2 intertrochanteric fractures following intramedullary fixation: a retrospective study based on computerised tomography findings
To determine how the reduction of medial and anteromedial cortices using CT findings in 31-A2 intertrochanteric fractures treated with the intramedullary nail could affect the clinical outcomes and complicatio...
-
Protocol
Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
Coordinated regeneration of melanocyte stem cells (McSCs) and hair follicle stem cells (HSCs) contributes to generation of pigmented hairs. Synchronous regeneration of McSCs with activation of HSCs occurs not ...
-
Article
Cyclic mechanical stretch enhances BMP9-induced osteogenic differentiation of mesenchymal stem cells
The purpose of this study was to investigate whether mechanical stretch can enhance the bone morphogenetic protein 9 (BMP9)-induced osteogenic differentiation in MSCs.
-
Article
Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration
Regeneration of hair follicles relies on activation of hair follicle stem cells during telogen to anagen transition process in hair cycle. This process is rigorously controlled by intrinsic and environmental f...
-
Article
Open AccessA validated preoperative score predicting survival and functional outcome in lung cancer patients operated with posterior decompression and stabilization for metastatic spinal cord compression
This study aims to create and validate a score for survival and functional outcome of lung cancer patients with metastatic spinal cord compression (MSCC) after posterior decompressive surgery.
-
Article
12-O-tetradecanoylphorbol-13-acetate activates hair follicle melanocytes for hair pigmentation via Wnt/β-catenin signaling
Melanocyte stem cells (McSCs) undergo cyclical activation and quiescence together with hair follicle stem cells (HFSCs). This process is strictly controlled by the autonomous and extrinsic signaling environmen...