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Article
Open AccessThe roles of autophagy, ferroptosis and pyroptosis in the anti-ovarian cancer mechanism of harmine and their crosstalk
This study aimed to investigate the role of autophagy, ferroptosis, and pyroptosis in the antitumour mechanism of harmine (Har) and its crosstalk in ovarian cancer. By transmission electron microscopy, we foun...
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Article
The relationship between parent–child communication and English academic engagement among middle school students: a moderated mediation model
This study constructed a moderated mediation model to explore the impact of parent–child communication on English academic engagement. We conducted a questionnaire survey among 21,270 middle school students us...
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Article
Effects of social support and positive psychology intervention on depression and subjective well-being among the left-behind children: a two-year longitudinal study
To explore the effects of social support and positive psychological intervention on subjective well-being and depression of left-behind children. 70 left-behind children with depression ...
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Article
Characteristics of mesenchymal stem cells and their exosomes derived from giant panda (Ailuropoda melanoleuca) endometrium
Conservation of genetic resources is an important way to protect endangered species. At present, mesenchymal stem cells (MSCs) have been isolated from the bone marrow and umbilical cords of giant pandas. Howev...
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Article
Landslide displacement prediction based on optimized empirical mode decomposition and deep bidirectional long short-term memory network
There are two technical challenges in predicting slope deformation. The first one is the random displacement, which could not be decomposed and predicted by numerically resolving the observed accumulated displ...
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Article
Dynamic prediction of landslide displacement using singular spectrum analysis and stack long short-term memory network
An accurate landslide displacement prediction is an important part of landslide warning system. Aiming at the dynamic characteristics of landslide evolution and the shortcomings of traditional static predictio...
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Article
Open AccessGenome-wide association studies provide insights into the genetic determination of fruit traits of pear
Pear is a major fruit tree crop distributed worldwide, yet its breeding is a very time-consuming process. To facilitate molecular breeding and gene identification, here we have performed genome-wide associatio...
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Article
Structure-Activity Relationship and Pharmacological Evaluation of 4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenylacetamide as Cholesterol Ester Transfer Protein Inhibitor
Cholesterol ester transfer protein is a plasma glycoprotein synthesized by the liver. Inhibitors of this protein have been researched to treat dyslipidemia. The purpose of this study was to use the computer-ai...
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Article
Open AccessA network pharmacology-based study on Alzheimer disease prevention and treatment of Qiong Yu Gao
As the pathological mechanisms of AD are complex, increasing evidence have demonstrated Chinese Medicine with multi-ingredients and multi-targets may be more suitable for the treatment of diseases with complex...
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Article
Association between serum/plasma adiponectin levels and immune-mediated diseases: a meta-analysis
Adiponectin plays an important role in the development of immune-mediated diseases. Currently published data regarding the relationship between serum/plasma levels of adiponectin and immune-mediated diseases a...
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Article
Open AccessDistinct transcriptome profiles reveal gene expression patterns during fruit development and maturation in five main cultivated species of pear (Pyrus L.)
The transcriptomes of five pear cultivars, ‘Hosui’ (P. pyrifolia), ‘Yali’ (P. bretschneideri), ‘Kuerlexiangli’ (P. sinkiangensis), ‘Nanguoli’ (P. ussuriensis) and ‘Starkrimson’ (P. communis) were sequenced at sev...
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Article
Expression differences of anthocyanin biosynthesis genes reveal regulation patterns for red pear coloration
This research reveals the different expression patterns of anthocyanin biosynthesis enzyme genes and transcription factors in six red-skinned pear cultivars with different genetic backgrounds. ...
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Article
A Novel Set of EST-Derived SSR Markers for Pear and Cross-Species Transferability in Rosaceae
Pear is a fruit species with worldwide distribution belonging to the Rosaceae family. In this study, transcriptomes of 12 different tissues of pear were newly assembled, with a total of 17,353 SSR loci identif...
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Article
Abdominal Lymph Node Metastasis in Patients with Mid Thoracic Esophageal Squamous Cell Carcinoma
There are few reports about abdominal lymph node metastasis of mid thoracic esophageal carcinoma. This study was designed to explore the pattern of abdominal lymph node metastasis in patients with mid thoracic...
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Article
Isomerization of Norbornadiene to Quadricyclane Using Ti-Containing MCM-41 as Photocatalysts
Heterogeneous Ti-containing MCM-41 materials were prepared for the photocatalytic isomerization of norbornadiene to quadricyclane with the aim of replacing homogeneous sensitizers. Chemical grafting produces q...
