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Article
Open AccessLow potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2
The renal epithelium is sensitive to changes in blood potassium (K+). We identify the basolateral K+ channel, Kir4.2, as a mediator of the proximal tubule response to K+ deficiency. Mice lacking Kir4.2 have a com...
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Article
SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis
Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy, necessitating further investigation into the underlying molecular mechanisms. This study aimed to elucidate the regulato...
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Article
Open AccessA Chinese adaptation of the Patient Health Questionnaire for Adolescents (PHQ-A): factor structure and psychometric properties
To examine the factor structure and psychometric properties of the Patient Health Questionnaire for Adolescents (PHQ-A) in Chinese children and adolescents with major depressive disorder (MDD).
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Article
Maintenance of callus-associated endophyte balance to mitigate oxidative browning in plant tissue culture practices
The frequently occurring browning of plant tissue cultures is a considerable problem in causing economic losses. However, the mechanism that causes browning of plant tissues is still controvesial and technolog...
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Article
Open AccessClonal hematopoiesis of indeterminate potential is associated with acute kidney injury
Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential (CHIP) confers increased ...
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Article
Open AccessAssociation between serum carotenoids and bacterial vaginosis infection among American women
Bacterial vaginosis (BV) is a widely occurring vaginal inflammation in women of childbearing age caused by dysbiosis of the vaginal flora. Few studies have investigated the effect of serum carotenoids on the d...
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Chapter and Conference Paper
Practical Research on AI Visual Focus Analysis in Online Teaching
This project aims to study learners’ visual focus in online learning and their behavior patterns when engaging with different learning media and cognitive processes. It uses AI models and data analysis methods...
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Chapter
Energy Justice Concerns of Nuclear Power in the 2025 Energy Transition Vision of Taiwan and Net Zero Roadmap of 2050
Energy justice emerged as a crosscutting social science research agenda aiming to apply justice to energy policy, energy production and systems, energy consumption, energy activism, energy security, and climat...
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Article
Open AccessEpidermal growth factor receptor activation is essential for kidney fibrosis development
Fibrosis is the progressive accumulation of excess extracellular matrix and can cause organ failure. Fibrosis can affect nearly every organ including kidney and there is no specific treatment currently. Althou...
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Article
Systematic analyzing a five- miRNA panel and its diagnostic value of plasma expression in colorectal cancer
Aberrant expression of miRNAs have been implicated in cancers, but the role of miRNAs in colorectal cancer (CRC) remains need to be elucidated. This study aimed to identify miRNAs that related to colorectal ca...
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Article
Open AccessRasch analysis of the Chinese version of the clinically useful depression outcome scale in patients with major depressive disorder
To examine the psychometric properties of the Chinese version of the Clinically Useful Depression Outcome Scale (CUDOS) in the Chinese patients with major depressive disorder (MDD) using Rasch analysis.
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Article
Open AccessOcellatuspyrones A‒G, new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
Marine invertebrates serve as rich sources of secondary metabolites with intriguing chemical diversities and a wide spectrum of biological activities. Particularly, marine shell-less sacoglossan mollusks have ...
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Article
Open AccessIdentification of autophagy-associated circRNAs in sepsis-induced cardiomyopathy of mice
Circular RNAs (circRNAs) play a role in sepsis-related autophagy. However, the role of circRNAs in autophagy after sepsis-induced cardiomyopathy (SICM) is unknown, so we explored the circRNA expression profile...
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Article
Open AccessContemplating the necessity of surgical treatment for posterior lenticonus: a case report
Posterior lenticonus is an uncommon congenital abnormality that causes a progressive, localized spherical or conical bulging of the posterior capsular membrane, resulting in an abnormal shape of the lens.
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Article
Enhanced energy density in polyetherimide nanocomposite film at high temperature induced by electrospun BaZrTiO3 nanofibers
Polymer dielectrics which possess excellent dielectric properties such as high breakdown strength, flexibility, and facile processability are considered as promising materials for advanced electrostatic capaci...
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Article
Identification of the CCL2 PI3K/Akt axis involved in autophagy and apoptosis after spinal cord injury
Spinal cord injury (SCI) is a devastating neurological disease with no cure that usually results in irreversible loss of sensory and voluntary motor functions below the injury site. We conducted an in-depth bi...
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Article
Enhanced mechanical performance of gradient-structured CoCrFeMnNi high-entropy alloys induced by industrial shot-blasting
In this study, CoCrFeMnNi high-entropy alloys (HEAs) with a surface gradient nanostructure were produced using industrial shot blasting, which improved their mechanical properties compared to the untreated all...
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Article
Open AccessIdentification of matrix-remodeling associated 5 as a possible molecular oncotarget of pancreatic cancer
Pancreatic cancer has an extremely poor prognosis. Here we examined expression, potential functions and underlying mechanisms of MXRA5 (matrix remodeling associated 5) in pancreatic cancer. Bioinformatics stud...
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Article
Open AccessThe mediating effect of distress tolerance on the relationship between stressful life events and suicide risk in patients with major depressive disorder
Despite widespread acknowledgment of the impact of stressful life events on suicide risk, the understanding of the psychological mechanisms underlying the relationship between stressful life events and suicide...
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Article
Open AccessGravitational Faraday effect from on-shell amplitudes
Effects of massive object’s spin on massive-massless 2 → 2 classical scattering is studied. Focus is set on the less-considered dimensionless expansion parameter λ/b, where λ is the massless particle’s wavelength...
