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  1. Article

    Open Access

    Invasive pulmonary aspergillosis among patients with severe community-acquired pneumonia and influenza in ICUs: a retrospective cohort study

    The prevalence, clinical characteristics, and outcomes of invasive pulmonary aspergillosis in patients with severe community-acquired pneumonia (CAP) in intensive care units remain underestimated because of th...

    Wei-Chun Lee, Che-Chia Chang, Meng-Chin Ho, Chieh-Mo Lin, Shaw-Woei Leu in Pneumonia (2024)

  2. Article

    Open Access

    Serum vascular endothelial growth factor affects tissue fluid accumulation and is associated with deteriorating tissue perfusion and oxygenation in severe sepsis: a prospective observational study

    Positive fluid balance and tissue fluid accumulation are associated with adverse outcomes in sepsis. Vascular endothelial growth factor (VEGF) increases in sepsis, promotes vascular permeability, and may affec...

    Chin-Kuo Lin, Ying-Huang Tsai, Kuo-Chin Kao in European Journal of Medical Research (2023)

  3. Article

    Open Access

    The association of aspirin use with overall survival of patients with inoperable non-small cell lung cancer: a retrospective study

    Studies have indicated that individuals taking aspirin have a reduced risk of cancers and have also established chemo-preventive benefit of aspirin in colorectal cancer. However, research on the association be...

    Min-Chun Chuang, Yao-Hsu Yang, Meng-Jer Hsieh, Yu-Ching Lin, Tsung-Ming Yang in BMC Cancer (2021)

  4. Article

    Open Access

    Author Correction: A highly sensitive and specific real-time quantitative PCR for BRAF V600E/K mutation screening

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Jrhau Lung, Ming‑Szu Hung, Yu‑Ching Lin, Yuan Yuan Jiang in Scientific Reports (2021)

  5. Article

    Open Access

    Artificial neural networks improve LDCT lung cancer screening: a comparative validation study

    This study proposes a prediction model for the automatic assessment of lung cancer risk based on an artificial neural network (ANN) with a data-driven approach to the low-dose computed tomography (LDCT) standa...

    Yin-Chen Hsu, Yuan-Hsiung Tsai, Hsu-Huei Weng, Li-Sheng Hsu, Ying-Huang Tsai in BMC Cancer (2020)

  6. Article

    Open Access

    A highly sensitive and specific real-time quantitative PCR for BRAF V600E/K mutation screening

    Mutations that lead to constitutive activation of key regulators in cellular processes are one of the most important drivers behind vigorous growth of cancer cells, and are thus prime targets in cancer treatme...

    Jrhau Lung, Ming-Szu Hung, Yu-Ching Lin, Yuan Yuan Jiang in Scientific Reports (2020)

  7. Article

    Open Access

    Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer

    Wnt-2 plays an oncogenic role in cancer, but which Frizzled receptor(s) mediates the Wnt-2 signaling pathway in lung cancer remains unclear. We sought to (1) identify and evaluate the activation of Wnt-2 signa...

    Dawn T Bravo, Yi-Lin Yang, Kristopher Kuchenbecker, Ming-Szu Hung, Zhidong Xu in BMC Cancer (2013)

  8. No Access

    Article

    WIF-1 promoter region hypermethylation as an adjuvant diagnostic marker for non-small cell lung cancer-related malignant pleural effusions

    Malignant pleural effusion is an important staging criterion in non-small cell lung cancer (NSCLC). Although cytologic examination remains the major diagnostic tool for NSCLC-related malignant pleural effusion...

    Tsung-Ming Yang, Shaw-Wei Leu, Jhy-Ming Li in Journal of Cancer Research and Clinical On… (2009)

  9. Article

    Open Access

    Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library

    Casein kinase 2 (CK2) is dysregulated in various human cancers and is a promising target for cancer therapy. To date, there is no small molecular CK2 inhibitor in clinical trial yet. With the aim to identify n...

    Ming-Szu Hung, Zhidong Xu, Yu-Ching Lin, Jian-Hua Mao, Cheng-Ta Yang in BMC Cancer (2009)