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  1. No Access

    Article

    The impact of needle location on clinical outcome of radiofrequency rhizotomy for trigeminal neuralgia

    Radiofrequency thermocoagulation trigeminal rhizotomy (RT-TR) through the foramen ovale is a minimally invasive treatment for trigeminal neuralgia. Navigation of magnetic resonance imaging (MRI) and CT fusion ...

    Wei-Chao Huang, Kuo-Tai Chen, Chih-Hao Kao, Jen-Tsung Yang in Acta Neurochirurgica (2022)

  2. Article

    Open Access

    Additive-manufactured Ti-6Al-4 V/Polyetheretherketone composite porous cage for Interbody fusion: bone growth and biocompatibility evaluation in a porcine model

    We developed a porous Ti alloy/PEEK composite interbody cage by utilizing the advantages of polyetheretherketone (PEEK) and titanium alloy (Ti alloy) in combination with additive manufacturing technology.

    Pei-I Tsai, Meng-Huang Wu, Yen-Yao Li, Tzu-Hung Lin in BMC Musculoskeletal Disorders (2021)

  3. Article

    Open Access

    Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells

    Glioblastoma multiforme (GBM) is the most severe type of primary brain tumor with a high mortality rate. Although extensive treatments for GBM, including resection, irradiation, chemotherapy and immunotherapy,...

    Jui-Chieh Chen, I-Neng Lee, Cheng Huang, Yu-** Wu, Chiu-Yen Chung in BMC Cancer (2019)

  4. Article

    Open Access

    Foramen ovale cannulation guided by intraoperative computed tomography with magnetic resonance image fusion plays a role in improving the long-term outcome of percutaneous radiofrequency trigeminal rhizotomy

    Percutaneous radiofrequency trigeminal rhizotomy (RF-TR) is a well-established treatment for patients suffering from trigeminal neuralgia (TN) as a primary modality or for those refractory to medical treatment...

    **-Jui Tsai, Ming-Hsueh Lee, Kuo-Tai Chen, Wei-Chao Huang in Acta Neurochirurgica (2019)

  5. No Access

    Article

    Percutaneous dorsal root ganglion block for treating lumbar compression fracture-related pain

    The pain of acute compression fracture in the lumbar spine may be refractory to conservative treatment, and surgery is not an optimal choice for the elderly or infirm individuals. Moreover, even vertebroplasty...

    Wei-Chao Huang, Martin Hsiu-Chu Lin, Ming-Hsueh Lee, Kuo-Tai Chen in Acta Neurochirurgica (2018)

  6. Article

    Open Access

    Effects of anti-epileptic drugs on spreading depolarization-induced epileptiform activity in mouse hippocampal slices

    Epilepsy and spreading depolarization (SD) are both episodic brain disorders and often exist together in the same individual. In CA1 pyramidal neurons of mouse hippocampal slices, induction of SD evoked epilep...

    Ching-Huei Lin, Shih-Pin Hsu, Ting-Chun Cheng, Chin-Wei Huang in Scientific Reports (2017)

  7. No Access

    Article

    Application of MRI and intraoperative CT fusion images with integrated neuronavigation in percutaneous radiofrequency trigeminal rhizotomy

    Percutaneous radiofrequency trigeminal rhizotomy (RF-TR) has been an effective treatment modality for medically refractory trigeminal neuralgia. Our group has established a protocol for this procedure that inc...

    Kuo-Tai Chen, Martin Hsiu-Chu Lin, Yuan-Hsiung Tsai, Ming-Hsueh Lee in Acta Neurochirurgica (2015)

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    Article

    Percutaneous dorsal root ganglion lysis with phenol for the treatment of pain associated with thoracic compression fracture

    Symptomatic thoracic compression fracture is one of the most common causes of back pain in elderly. Although vertebroplasty is widely utilized in patients when conservative treatment fails, we introduced an al...

    Chun-Hsien Lin, Ming-Hsueh Lee, Martin Hsiu-Chu Lin in Acta Neurochirurgica (2013)

  9. No Access

    Article

    Chronic cigarette smoke exposure enhances brain-derived neurotrophic factor expression in rats with traumatic brain injury

    The involvement of brain-derived neurotrophic factor (BDNF) in regulating neuronal survival during neuron differentiation, growth, and maturation, and during the regeneration of injured nerve cells, has alread...

    I-Neng Lee, Martin Hsiu-Chu Lin, Chiu-Yen Chung, Ming-Hsueh Lee in Metabolic Brain Disease (2012)

  10. No Access

    Article

    Foramen ovale cannulation guided by intra-operative computed tomography with integrated neuronavigation for the treatment of trigeminal neuralgia

    Radiofrequency rhizotomy of the Gasserian ganglion for the treatment of trigeminal neuralgia via percutaneous cannulation of the foramen ovale is facilitated by various localization modalities. In our prelimin...

    Martin Hsiu-Chu Lin, Ming-Hsueh Lee, Ting-Chung Wang, Yu-Kai Cheng in Acta Neurochirurgica (2011)