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Article

DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5′ leaders

Half of mammalian transcripts contain short upstream open reading frames (uORFs) that potentially regulate translation of the downstream coding sequence (CDS). The molecular mechanisms governing these events r...

Ramona Weber, Leon Kleemann, Insa Hirschberg, Min-Yi Chung… in Nature Communications (2022)