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Open AccessGenetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury
The long-term functional recovery of traumatic brain injury (TBI) is hampered by pathological events, such as parenchymal neuroinflammation, neuronal death, and white matter injury. Krüppel-like transcription ...
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Article
Open AccessNon-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders
The blood–brain barrier (BBB) is an essential component of the neurovascular unit that controls the exchanges of various biological substances between the blood and the brain. BBB damage is a common feature of...
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Article
Open AccessNeural stem cell therapy for subacute and chronic ischemic stroke
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a worldwide leading c...
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Article
Open AccessHuman neural stem cells rapidly ameliorate symptomatic inflammation in early-stage ischemic-reperfusion cerebral injury
Clinically, a good deal of injury from stroke results from ischemic-reperfusion. There is a loss of cerebral parenchyma and its associated cells, disruption of neuronal connections, compromise of the blood-bra...
