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  1. No Access

    Article

    Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1

    Immunotherapy with anti-GD2 antibodies has advanced the treatment of children with high-risk neuroblastoma, but nearly half of patients relapse, and little is known about mechanisms of resistance to anti-GD2 t...

    Nathaniel W. Mabe, Min Huang, Guillermo N. Dalton, Gabriela Alexe… in Nature Cancer (2022)

  2. No Access

    Article

    Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

    The disialoganglioside GD2 is overexpressed on several solid tumors, and monoclonal antibodies targeting GD2 have substantially improved outcomes for children with high-risk neuroblastoma. However, approximate...

    Johanna Theruvath, Marie Menard, Benjamin A. H. Smith, Miles H. Linde… in Nature Medicine (2022)