1 Result(s)

Article

Mycobacterium tuberculosis expressing phospholipase C subverts PGE₂ synthesis and induces necrosis in alveolar macrophages

Phospholipases C (PLCs) are virulence factors found in several bacteria. In Mycobacterium tuberculosis (Mtb) they exhibit cytotoxic effects on macrophages, but the mechanisms involved in PLC-induced cell death ar...

Patricia A Assis, Milena S Espíndola, Francisco WG Paula-Silva… in BMC Microbiology (2014)