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    Ex vivo therapy of malignant melanomas transplanted into organotypic brain slice cultures using inhibitors of histone deacetylases

    Disease progression in patients suffering from malignant melanomas is often determined by metastatic spreading into brain parenchyma. Systemic chemotherapy regimens are, therefore, mandatory for successful tre...

    Annett Hölsken, Ilker Y. Eyüpoglu, Mike Lueders, Christian Tränkle in Acta Neuropathologica (2006)