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  1. Article

    Open Access

    Predicting work disability among people with chronic conditions: a prospective cohort study

    Few risk prediction scores are available to identify people at increased risk of work disability, particularly for those with an existing morbidity. We examined the predictive performance of disability risk sc...

    Solja T. Nyberg, Jaakko Airaksinen, Jaana Pentti, Jenni Ervasti in Scientific Reports (2023)

  2. Article

    Open Access

    Psychosocial work environment as a dynamic network: a multi-wave cohort study

    While characteristics of psychosocial work environment have traditionally been studied separately, we propose an alternative approach that treats psychosocial factors as interacting elements in networks where ...

    Marko Elovainio, Christian Hakulinen, Kaisla Komulainen in Scientific Reports (2022)

  3. Article

    Open Access

    Association of sleep duration in middle and old age with incidence of dementia

    Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration prior to old age is associated with dementia incidence. Using data from 7959 participants of the Whitehall II study, w...

    Séverine Sabia, Aurore Fayosse, Julien Dumurgier in Nature Communications (2021)

  4. Article

    Open Access

    Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies

    Individuals experiencing socioeconomic disadvantage in childhood have a higher rate of inflammation-related diseases decades later. Little is known about the mechanisms linking early life experiences to the fu...

    Cristian Carmeli, Zoltán Kutalik, Pashupati P. Mishra, Eleonora Porcu in Scientific Reports (2021)

  5. Article

    Open Access

    The association between accelerometer-assessed physical activity and respiratory function in older adults differs between smokers and non-smokers

    The association between physical activity and lung function is thought to depend on smoking history but most previous research uses self-reported measures of physical activity. This cross-sectional study inves...

    Mohamed Amine Benadjaoud, Mehdi Menai, Vincent T. van Hees in Scientific Reports (2019)

  6. Article

    Open Access

    Multi-cohort study identifies social determinants of systemic inflammation over the life course

    Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation...

    Eloïse Berger, Raphaële Castagné, Marc Chadeau-Hyam in Nature Communications (2019)

  7. Article

    Open Access

    Author Correction: Development and validation of a risk prediction model for work disability: multicohort study

    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

    Jaakko Airaksinen, Markus Jokela, Marianna Virtanen, Tuula Oksanen in Scientific Reports (2018)

  8. Article

    Open Access

    Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies

    Diet may modify metabolomic profiles towards higher or lower cardiovascular disease (CVD) risk. We aimed to identify metabolite profiles associated with high adherence to dietary recommendations - the Alternat...

    Tasnime Akbaraly, Peter Würtz, Archana Singh-Manoux in Scientific Reports (2018)

  9. Article

    Open Access

    Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study

    The allostatic load index quantifies the cumulative multisystem physiological response to chronic everyday stress, and includes cardiovascular, metabolic and inflammatory measures. Despite its central role in ...

    Enikő Zsoldos, Nicola Filippini, Abda Mahmood, Clare E. Mackay in Scientific Reports (2018)

  10. Article

    Open Access

    Development and validation of a risk prediction model for work disability: multicohort study

    Work disability affects quality of life, earnings, and opportunities to contribute to society. Work characteristics, lifestyle and sociodemographic factors have been associated with the risk of work disability...

    Jaakko Airaksinen, Markus Jokela, Marianna Virtanen, Tuula Oksanen in Scientific Reports (2017)

  11. Article

    Open Access

    Work stress, anthropometry, lung function, blood pressure, and blood-based biomarkers: a cross-sectional study of 43,593 French men and women

    Work stress is a risk factor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile of individuals with work stress. To address this limitation, we conducted a cross-sect...

    Linda L. Magnusson Hanson, Hugo Westerlund, Marcel Goldberg in Scientific Reports (2017)

  12. Article

    Open Access

    Work disability before and after a major cardiovascular event: a ten-year study using nationwide medical and insurance registers

    We examined the trajectories of work disability before and after IHD and stroke events. New IHD (n = 13521) and stroke (n = 7162) cases in 2006–2008 were retrieved from nationwide Swedish hospital records and ...

    Marianna Virtanen, Jenni Ervasti, Ellenor Mittendorfer-Rutz in Scientific Reports (2017)

  13. Article

    Open Access

    Lifecourse socioeconomic status and type 2 diabetes: the role of chronic inflammation in the English Longitudinal Study of Ageing

    We examined the association between lifecourse socioeconomic status (SES) and the risk of type 2 diabetes at older ages, ascertaining the extent to which adult lifestyle factors and systemic inflammation expla...

    Silvia Stringhini, Paola Zaninotto, Meena Kumari, Mika Kivimäki in Scientific Reports (2016)