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  1. Article

    Open Access

    Effect of early vs. delayed extubation on functional outcome among patients with acute ischemic stroke treated with endovascular thrombectomy under general anesthesia: the prospective, randomized controlled EDESTROKE trial study protocol

    Recent meta-analyses and randomized studies have shown that among patients with acute ischemic stroke undergoing endovascular thrombectomy, general anesthesia with mechanical ventilation is associated with bet...

    Manuel Taboada, Ana Estany-Gestal, Jorge Fernández, Laura Barreiro, Kora Williams in Trials (2024)

  2. Article

    Open Access

    A comparative analysis of the intrauterine transcriptome in fertile and subfertile mares using cytobrush sampling

    Subfertility is a major problem in modern horse breeding. Especially, mares without clinical signs of reproductive diseases, without known uterine pathogens and no evidence of inflammation but not becoming pre...

    Katharina S. Weber, Karen Wagener, Miguel Blanco, Stefan Bauersachs in BMC Genomics (2021)

  3. Article

    Open Access

    High diversity and variability of pipolins among a wide range of pathogenic Escherichia coli strains

    Self-synthesizing transposons are integrative mobile genetic elements (MGEs) that encode their own B-family DNA polymerase (PolB). Discovered a few years ago, they are proposed as key players in the evolution ...

    Saskia-Camille Flament-Simon, María de Toro, Liubov Chuprikova in Scientific Reports (2020)

  4. No Access

    Article

    Association between periodontitis and ischemic stroke: a systematic review and meta-analysis

    Several observational studies have suggested an association between periodontitis and cerebral ischemia. This meta-analysis aimed to investigate whether this link exists, and if so, the degree to which it is s...

    Yago Leira, Juan Seoane, Miguel Blanco in European Journal of Epidemiology (2017)

  5. Article

    Open Access

    Increased Endothelial Progenitor Cell Levels are Associated with Good Outcome in Intracerebral Hemorrhage

    Circulating endothelial progenitor cells (EPCs) play a role in the regeneration of damaged brain tissue. However, the relationship between circulating EPC levels and functional recovery in intracerebral hemorr...

    Juan Pías-Peleteiro, María Pérez-Mato, Esteban López-Arias in Scientific Reports (2016)

  6. Article

    Open Access

    Study of Protein Expresion in Peri-Infarct Tissue after Cerebral Ischemia

    In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectr...

    David Brea, Jesús Agulla, An Staes, Kris Gevaert, Francisco Campos in Scientific Reports (2015)

  7. Article

    Open Access

    Interleukin-10 facilitates the selection of patients for systemic thrombolysis

    Clinical-Diffusion mismatch (CDM; NIHSS score ≥8 & DWI lesion volume ≤25 mL) and Perfusion-Diffusion mismatch (PDM; difference >20% between initial DWI and MTT lesion volumes) have been proposed as surrogates ...

    Manuel Rodríguez-Yáñez, Mar Castellanos, Tomás Sobrino, David Brea in BMC Neurology (2013)

  8. No Access

    Article

    Major advances in the treatment of stroke

    Several clinical trials and experimental studies that could have a major impact on the treatment of patients with ischaemic stroke were published in 2012. The studies cover all therapeutic options, including s...

    Miguel Blanco, José Castillo in Nature Reviews Neurology (2013)

  9. No Access

    Article

    Endovascular treatment of an acutely ruptured intracranial aneurysm in pregnancy: report of eight cases

    Treatment of acutely ruptured intracranial aneurysms in pregnancy represents a clinical challenge requiring a meticulously selected strategy. We report eight cases of ruptured cerebral aneurysms in eight pregn...

    José Manuel Pumar, Maria I. Pardo, Jose M. Carreira, Jose Castillo in Emergency Radiology (2010)

  10. Article

    Open Access

    Erratum to: Invasiveness as a putative additional virulence mechanism of some atypical Enteropathogenic Escherichia coli strains with different uncommon intimin types

    Denise Yamamoto, Rodrigo T Hernandes, Miguel Blanco, Lilo Greune in BMC Microbiology (2009)

  11. Article

    Open Access

    Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli(AIEC)

    Crohn's disease (CD) is a high morbidity chronic inflammatory disorder of unknown aetiology. Adherent-invasive Escherichia coli (AIEC) has been recently implicated in the origin and perpetuation of CD. Because ba...

    Margarita Martinez-Medina, Plínio Naves, Jorge Blanco, Xavier Aldeguer in BMC Microbiology (2009)

  12. Article

    Open Access

    Invasiveness as a putative additional virulence mechanism of some atypical Enteropathogenic Escherichia colistrains with different uncommon intimin types

    Enteropathogenic Escherichia coli (EPEC) produce attaching/effacing (A/E) lesions on eukaryotic cells mediated by the outer membrane adhesin intimin. EPEC are sub-grouped into typical (tEPEC) and atypical (aEPEC)...

    Denise Yamamoto, Rodrigo T Hernandes, Miguel Blanco, Lilo Greune in BMC Microbiology (2009)

  13. Article

    Open Access

    Extraintestinal pathogenic Escherichia coliO1:K1:H7/NM from human and avian origin: detection of clonal groups B2 ST95 and D ST59 with different host distribution

    Extraintestinal pathogenic Escherichia coli (ExPEC) strains of serotype O1:K1:H7/NM are frequently implicated in neonatal meningitis, urinary tract infections and septicemia in humans. They are also commonly isol...

    Azucena Mora, Cecilia López, Ghizlane Dabhi, Miguel Blanco in BMC Microbiology (2009)

  14. Article

    Open Access

    Serotypes, virulence genes and intimin types of Shiga toxin (verocytotoxin)-producing Escherichia coli isolates from minced beef in Lugo (Spain) from 1995 through 2003

    Shiga toxin-producing Escherichia coli (STEC) have emerged as pathogens that can cause food-borne infections and severe and potentially fatal illnesses in humans, such as haemorrhagic colitis (HC) and haemolytic ...

    Azucena Mora, Miguel Blanco, Jesús E Blanco, Ghizlane Dahbi in BMC Microbiology (2007)

  15. Article

    Open Access

    Serotypes, virulence genes, and PFGE profiles of Escherichia coliisolated from pigs with postweaning diarrhoea in Slovakia

    Postweaning diarrhoea (PWD) in pigs is usually the main infectious problem of large-scale farms and is responsible for significant losses worldwide. The disease is caused mainly by enterotoxigenic E. coli (ETEC) ...

    Hung Vu Khac, Emil Holoda, Emil Pilipcinec, Miguel Blanco in BMC Veterinary Research (2006)

  16. Article

    Open Access

    Depression in acute phase of ischemic stroke: frequency and associated factors

    Isabel Jiménez-Martín, Manuel Rodríguez-Yáñez in Annals of General Psychiatry (2006)

  17. Article

    Open Access

    Serotypes, intimin variants and other virulence factors of eae positive Escherichia coli strains isolated from healthy cattle in Switzerland. Identification of a new intimin variant gene (eae-η2)

    Enteropathogenic Escherichia coli (EPEC) and Shigatoxin-producing Escherichia coli (STEC) share the ability to introduce attaching-and-effacing (A/E) lesions on intestinal cells. The genetic determinants for the ...

    Miguel Blanco, Sandra Schumacher, Taurai Tasara, Claudio Zweifel in BMC Microbiology (2005)

  18. Article

    Open Access

    First isolation and further characterization of enteropathogenic Escherichia coli (EPEC) O157:H45 strains from cattle

    Enteropathogenic Escherichia coli (EPEC), mainly causing infantile diarrhoea, represents one of at least six different categories of diarrheagenic E. coli with corresponding distinct pathogenic schemes. The mecha...

    Roger Stephan, Nicole Borel, Claudio Zweifel, Miguel Blanco in BMC Microbiology (2004)

  19. Article

    Open Access

    First isolation of the enterohaemorrhagic Escherichia coli O145:H- from cattle in feedlot in Argentina

    Enterohaemorrhagic Escherichia coli (EHEC) is considered to be common cause of haemorrhagic colitis (HC), thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome (HUS) in humans. In a previous paper, ...

    Nora L Padola, Marcelo E Sanz, Paula MA Lucchesi, Jesús E Blanco in BMC Microbiology (2002)

  20. No Access

    Article

    HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex

    The mammalian HBP2 gene has been isolated by functional complementation of cells unable to undergo DNA replication in fission yeast. HBP2 is a protein with a high mobility group (HMG) domain that belongs to the ...

    Alberto Sánchez-Díaz, Miguel Blanco, Nic Jones, Sergio Moreno in Current Genetics (2001)

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