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Article
Effects of anti-SARS-CoV-2 vaccination in living kidney transplant recipients prior to transplantation
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Article
Open AccessEvolution of Humanity
In 1952, Kinji Imanishi wrote a thought-provoking essay on the nature of animal societies. In this essay, he applied the concept of human culture (which he referred to as Karuchua) to nonhuman animals by giving d...
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Article
Utility of a Passive Bending Colonoscope for Endoscopic Retrograde Cholangiopancreatography in Patients with Surgically Altered Anatomy
The utility of a passive bending colonoscope (PBCS) in ERCP for patients with surgically altered anatomy has not been established. This study compared the outcome of PBCS-ERCP and balloon-assisted enteroscope ...
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Article
Open AccessDevelopment and nationwide validation of kidney graft injury markers using urinary exosomes and microvesicles (complete English translation of the Japanese version)
Non-invasive, prompt, and proper detection tools for kidney graft injuries (KGIs) are awaited to ensure graft longevity. We screened diagnostic biomarkers for KGIs following kidney transplantation using extrac...
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Article
Open AccessFeasibility of edoxaban for asymptomatic cancer-associated thrombosis in Japanese patients with gastrointestinal cancer: ExCAVE study
Although initial therapy with a parenteral anticoagulant is required before edoxaban, this strategy is frequently avoided in actual clinical practice because of its complexity. This study assessed the feasibil...
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Article
Open AccessDecision making for anti-VEGF inhibitor continuation: dip stick? or urine protein/creatinine ratio? (VERSiON UP study)
Monitoring proteinuria is important for the management of patients with cancer treated with anti-vascular endothelial growth factor (VEGF) or anti-VEGF receptor (VEGFR) inhibitors (VEGF/Ri). Here we investigat...
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Article
Post-kidney transplant soluble Klotho levels are determined by pretransplant soluble Klotho levels in both living donors and recipients
Soluble Klotho (sKl), the free form of membrane-bound Klotho predominantly expressed in the kidney, is detectable in serum and may have multiple pleiotropic effects. Patients with end-stage kidney disease are ...
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Article
Skeletal and mineral metabolic effects of risedronate in a rat model of high-turnover renal osteodystrophy
High-turnover bone disease is a major consequence of SHPT and may explain the high risk for fracture in patients with advanced chronic kidney disease (CKD). Bisphosphonates suppress bone turnover and improve b...
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Article
Longitudinal changes in the targets of chimpanzee (Pan troglodytes) hunts at Mahale Mountains National Park: how and why did they begin to intensively hunt red colobus (Piliocolobus rufomitratus) in the 1980s?
The hunting activities of chimpanzees (Pan troglodytes) at Mahale Mountains National Park exhibited a significant change over a 46-year observation period, shifting from sporadic hunting for small ungulates and p...
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Article
Correction to: Preventive effect of early introduction of everolimus and reduced‑exposure tacrolimus on renal interstitial fibrosis in de novo living‑donor renal transplant recipients
In the Original publication of the article, the co-author name has been misspelled as “Yousuke Nakagawa”.
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Article
Preventive effect of early introduction of everolimus and reduced-exposure tacrolimus on renal interstitial fibrosis in de novo living-donor renal transplant recipients
To improve the long-term outcomes following renal transplantation, prevention of renal-allograft interstitial fibrosis (IF), mainly due to calcineurin inhibitors, is an important therapeutic target. Everolimus...
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Article
Open AccessTrends of kidney transplantation in Japan in 2018: data from the kidney transplant registry
The number of kidney transplants has gradually increased in the last decade; it was 1742 in Japan in 2017. The outcomes have improved year by year, with the indications for transplantation expanding accordingl...
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Article
Open AccessStudy protocol of HGCSG1404 SNOW study: a phase I/II trial of combined chemotherapy of S-1, nab-paclitaxel and oxaliplatin administered biweekly to patients with advanced gastric cancer
In Japan, S-1 plus cisplatin (SP) regimen has become a standard therapy for patients with advanced gastric cancer. Moreover, the S-1 plus oxaliplatin regimen is now a standard treatment.
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Article
Open AccessA Phase I Study of Combination Therapy with Sorafenib and 5-Fluorouracil in Patients with Advanced Hepatocellular Carcinoma
Sorafenib is the first molecular targeted drug approved for the treatment of advanced hepatocellular carcinoma (HCC) and is a potent small molecule inhibitor of multiple kinases. Combination therapy with soraf...
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Article
What volume of seeds can a chimpanzee carry in its body?
Great apes are important seed dispersers with large bodies, able to swallow large seeds and travel long distances. Although there have been several studies investigating seed dispersal quality [sensu Schupp (V...
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Article
An observation of a severely disabled infant chimpanzee in the wild and her interactions with her mother
We report the physical and behavioral development of one severely disabled female infant chimpanzee (Pan troglodytes schweinfurthii) of the well-habituated M group in the Mahale Mountains National Park. We docume...
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Article
Mineral and bone disorders in kidney transplant recipients: reversible, irreversible, and de novo abnormalities
Given the advances in medical technologies related to kidney transplantation, the post-transplant graft survival rate and quality of life have improved dramatically. Nevertheless, post-transplant mortality rat...
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Article
A case of right renal artery originating from the thoracic aorta
The renal arteries normally originate from the abdominal aorta between the first and second lumbar vertebrae. The main renal artery arising from the thoracic aorta is an uncommon anomaly. Here we report a rare...
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Article
Lethal aggression in Pan is better explained by adaptive strategies than human impacts
A meta-analysis of studies on chimpanzees and bonobos across Africa shows that their conspecific aggression is the normal and expected product of adaptive strategies to obtain resources or mates and has no con...
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Chapter
Social Touch in Apes and Dolphins
Social touch, or physical contact among two or more individuals in a nonaggressive context, seems to play important roles among both primates and cetaceans. However, with exception of social grooming among pri...
