8 Result(s)
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Article
Open AccessThe swan genome and transcriptome, it is not all black and white
The Australian black swan (Cygnus atratus) is an iconic species with contrasting plumage to that of the closely related northern hemisphere white swans. The relative geographic isolation of the black swan may hav...
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Article
Open AccessInsights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto
Bats are an extremely successful group of mammals and possess a variety of unique characteristics, including their ability to co-exist with a diverse range of pathogens. The major histocompatibility complex (M...
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Article
Open AccessMarsupials and monotremes possess a novel family of MHC class I genes that is lost from the eutherian lineage
Major histocompatibility complex (MHC) class I genes are found in the genomes of all jawed vertebrates. The evolution of this gene family is closely tied to the evolution of the vertebrate genome. Family membe...
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Open AccessProteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis
Bats are a major reservoir of emerging infectious viruses. Many of these viruses are highly pathogenic to humans however bats remain asymptomatic. The mechanism by which bats control viral replication is unkno...
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Open AccessCharacterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing
Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infecti...
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Open AccessThe immune gene repertoire of an important viral reservoir, the Australian black flying fox
Bats are the natural reservoir host for a range of emerging and re-emerging viruses, including SARS-like coronaviruses, Ebola viruses, henipaviruses and Rabies viruses. However, the mechanisms responsible for ...
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Open AccessComparative genomic analysis and evolution of the T cell receptor loci in the opossum Monodelphis domestica
All jawed-vertebrates have four T cell receptor (TCR) chains: alpha (TRA), beta (TRB), gamma (TRG) and delta (TRD). Marsupials appear unique by having an additional TCR: mu (TRM). The evolutionary origin of TR...
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Open AccessAnalysis of a set of Australian northern brown bandicoot expressed sequence tags with comparison to the genome sequence of the South American grey short tailed opossum
Expressed sequence tags (ESTs) have been used for rapid gene discovery in a variety of organisms and provide a valuable resource for whole genome annotation. Although the genome of one marsupial, the opossum Mono...
