-
Article
Open AccessRetrospective analysis of acute HBV infections occurred in 1978–79 and 1994–95 in North-East Italy: increasing prevalence of BCP/pre-core mutants in sub-genotype D3
At the end of the 1970s, in Italy more than 2% of the general population was HBsAg carrier. In the late ‘70s and late ‘80s, two remarkable events might have impacted on HBV strains transmitted in North-East It...
-
Article
Open AccessHepatitis a virus genotypes and strains from an endemic area of Europe, Bulgaria 2012–2014
Hepatitis A virus (HAV) infection is endemic in Eastern European and Balkan region countries. In 2012, Bulgaria showed the highest rate (67.13 cases per 100,000) in Europe. Nevertheless, HAV genotypes and stra...
-
Article
Open AccessMulti-drug resistant Klebsiella pneumoniae strains circulating in hospital setting: whole-genome sequencing and Bayesian phylogenetic analysis for outbreak investigations
Carbapenems resistant Enterobacteriaceae infections are increasing worldwide representing an emerging public health problem. The application of phylogenetic and phylodynamic analyses to bacterial whole genome seq...
-
Article
Open AccessErratum to: Molecular epidemiology and phylogenetic analysis of Hepatitis B virus in a group of migrants in Italy
-
Article
Open AccessNaturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C
The detection of baseline resistance mutations to new direct-acting antivirals (DAAs) in HCV chronically infected treatment-naïve patients could be important for their management and outcome prevision. In this...
-
Article
Open AccessMolecular epidemiology and phylogenetic analysis of Hepatitis B virus in a group of migrants in Italy
Hepatitis B virus infection (HBV) is widespread and it is considered a major health problem worldwide. The global distribution of HBV varies significantly between countries and between regions of the world. Am...
-
Article
Open AccessMigration pattern of hepatitis A virus genotype IA in North-Central Tunisia
Hepatitis A virus (HAV) epidemiology in Tunisia has changed from high to intermediate endemicity in the last decades. However, several outbreaks continue to occur. The last reported sequences from Tunisian HAV...
-
Article
Open AccessSurveillance of hepatitis A virus in urban sewages and comparison with cases notified in the course of an outbreak, Italy 2013
Over the past 20 years, Hepatitis A notifications in Italy have been in decline. Since the beginning of 2013 however, Italy has been experiencing a foodborne hepatitis A outbreak caused by genotype IA, involvi...
-
Article
Open AccessMolecular characterisation of human hepatitis E virus from Italy: comparative analysis of five reverse transcription-PCR assays
Hepatitis E (HEV) is an important public-health concern as a major cause of enterically transmitted hepatitis worldwide. In industrialised countries it is considered rare, and largely confined to travellers re...
-
Article
Open AccessMicrobiological and 16S rRNA analysis of sulphite-reducing clostridia from river sediments in central Italy
Microbiological indicators are commonly used in the assessment of public health risks associated with fecal contamination of freshwater ecosystems. Sediments are a reservoir of microorganisms, and can thus pro...
-
Article
Expression and Membrane Association of Hepatitis C Virus Envelope 1 Protein
The expression of hepatitis C virus (HCV) E1 protein is toxic for Escherichia coli cells. For this reason, we have cloned the E1 gene in the pET3a vector and analyzed the inducible expression of the protein in...
