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    Studying DNATopoisomerase I-Targeted Drugs In the Yeast

    The budding yeast Saccharomyces cerevisiae has been a valuable model in establishing eukaryotic DNA topoisomerase I as the cellular target of specific antineoplastic agents, including camptothecin (1–3), aclacino...

    Michael H. Woo, John R. Vance, Mary-Ann Bjornsti in DNA Topoisomerase Protocols (2001)