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  1. Article

    Open Access

    Clinical characteristics and management of patients with nonalcoholic steatohepatitis in a real-world setting: analysis of the Ipsos NASH therapy monitor database

    Nonalcoholic steatohepatitis (NASH) is the more severe, inflammatory type of nonalcoholic fatty liver disease (NAFLD). NASH, a leading indication for liver transplantation, is growing in prevalence. The extent...

    Karishma Shelley, Amy Articolo, Rakesh Luthra, Michael Charlton in BMC Gastroenterology (2023)

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  2. No Access

    Article

    Nonalcoholic fatty liver disease: impact on healthcare resource utilization, liver transplantation and mortality in a large, integrated healthcare system

    NAFLD is the most prevalent liver disease globally, affecting 20% of the world population. Healthcare resource utilization (HRU) attributable to NAFLD has been difficult to define.

    Thomas Gerard Cotter, Li Dong, John Holmen, Richard Gilroy… in Journal of Gastroenterology (2020)

  3. No Access

    Article

    Liver Allocation Policies in the USA: Past, Present, and the Future

    Identifying the optimal allocation policy with regard to hepatocellular carcinoma has been a persistent and evolving challenge. The current criteria for LT for HCC endorsed by the United Network of Organ Shari...

    Anjana Pillai, Thomas Couri, Michael Charlton in Digestive Diseases and Sciences (2019)

  4. No Access

    Article

    Surgical Issues in NASH: Bariatric Surgery and Liver Transplantation

    The rising prevalence of obesity in general and non-alcoholic steatohepatitis (NASH) specifically as an indication for liver transplantation has occurred in parallel with an increase in the consideration and p...

    Sonali Paul, Michael Charlton in Current Hepatology Reports (2018)

  5. No Access

    Article

    Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah

    Biliary tract cancers (BTC) including, cholangiocarcinoma (CC) and gallbladder cancer (GBC), are rare and highly fatal malignancies. The etiology and inherited susceptibility of both malignancies are poorly un...

    N. Jewel Samadder, Ken Robert Smith, Jathine Wong… in Digestive Diseases and Sciences (2016)

  6. No Access

    Article

    An Update of Liver Transplantation for Nonalcoholic Steatohepatitis

    Nonalcoholic steatohepatitis (NASH), obesity, and the metabolic syndrome are highly prevalent before and after liver transplantation, with NASH currently the second most common indication. This review consider...

    I. Raymond Thomason, Michael Charlton in Current Hepatology Reports (2015)

  7. No Access

    Article

    Genetic Variation in the Peroxisome Proliferator Activated Receptor-Gamma Gene Is Associated with Histologically Advanced NAFLD

    The peroxisome proliferator activated receptor-gamma (PPARG) is a nuclear receptor that regulates adipocyte differentiation, insulin sensitivity and lipid metabolism, thus, it represents a good candidate gene for...

    Samer Gawrieh, Miranda C. Marion, Richard Komorowski… in Digestive Diseases and Sciences (2012)

  8. No Access

    Article

    Branched-chain amino-acid granules: can they improve survival in patients with liver cirrhosis?

    Michael Charlton in Nature Clinical Practice Gastroenterology & Hepatology (2006)