-
Article
Open AccessPhenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study
The role of site of infection in sepsis has been poorly characterized. Additionally, sepsis epidemiology has evolved. Early mortality has decreased, but many survivors now progress into chronic critical illnes...
-
Article
Open AccessMyeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis
Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circula...
-
Article
Open AccessBrief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma
Genes encoding TRK are oncogenic drivers in multiple tumour types including infantile fibrosarcoma, papillary thyroid cancer and high-grade gliomas (HGG). TRK fusions have a critical role in tumourigenesis in ...
-
Article
Phase II trial of ixabepilone, an epothilone B analog, given daily for three days every three weeks, in metastatic breast cancer
Twelve patients with metastatic breast cancer previously exposed to taxanes were treated on a Phase II trial with ixabepilone. Eligible patients had histologically confirmed metastatic breast cancer with measu...
-
Article
Gleason score and pretreatment prostate-specific antigen in survival among patients with stage D2 prostate cancer
Although multiple studies have addressed the prognostic importance of tumor differentiation in patients with clinically localized prostate cancer, few data are available in patients with metastatic disease. We...
-
Article
An Elementary Interpretation of Science
-
Article
[Book Reviews]
Systematic Qualitative Analysis
-
Article
Youth Science Encyclopædia
Junior Science Encyclopaedia
-
Article
[Book Reviews]
Organic Chemistry Today
